ID   A0A3Q0KLB3_SCHMA        Unreviewed;       487 AA.
AC   A0A3Q0KLB3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=G_PROTEIN_RECEP_F1_2 domain-containing protein {ECO:0000313|WBParaSite:Smp_127860.1};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_127860.1};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_127860.1}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_127860.1};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q0KLB3; -.
DR   STRING; 6183.A0A3Q0KLB3; -.
DR   EnsemblMetazoa; Smp_127860.1; Smp_127860.1; Smp_127860.
DR   WBParaSite; Smp_127860.1; Smp_127860.1; Smp_127860.
DR   InParanoid; A0A3Q0KLB3; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008528; F:G protein-coupled peptide receptor activity; IEA:InterPro.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR019427; 7TM_GPCR_serpentine_rcpt_Srw.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   PANTHER; PTHR46641:SF2; FMRFAMIDE RECEPTOR; 1.
DR   PANTHER; PTHR46641; FMRFAMIDE RECEPTOR-RELATED; 1.
DR   Pfam; PF10324; 7TM_GPCR_Srw; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        71..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        251..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        438..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          83..460
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   487 AA;  55954 MW;  695C3C14E41F8137 CRC64;
     MSNYTNLYLF NHHHPNTTST TSTTPTTTNT TNPTTNTTYI IPIPLSNHDN DINIEYLDNI
     LNIMRLICGK ILTPILCMIG ILSNIINIII LTREWMNSST NIYLTAVSIC DLLYLLFTYL
     FSLWLYPYIK QFTIYAYSIT IIHGTANLFS NITTWLTVSF TLERYIVISL PIISKKYCNK
     QRAIYIIIII FISCFILTLP DYLKKTIIYN NTTYNYNSSL NSNTKNVTIN NQYIVVDTNI
     NIILIKIGYD YINQIIFIIL PMILLIIFNS LLIRSVMKAN QDRKILIKHN NNHTNNTSIN
     MINDPKNIDL LHSNNNNNND NNNDGRKYSL VQLNQEATTS QMIPAIVRDA LEASMRTTIG
     ITSGITQSFR PIQYQTNLLP IITIKRNKLG EQQRITLMLI TIVIAFVLLQ LPSIVPTITI
     NLINAGIIQS TQYTTKCLLI YSNISNVLLI INAALNFVFY SLFSKKFRQT CYILLKNITC
     LKYFSYH
//