ID   A0A3Q0KNG3_SCHMA        Unreviewed;      1104 AA.
AC   A0A3Q0KNG3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2023, sequence version 2.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Transcriptional enhancer factor (Tef) related {ECO:0000313|WBParaSite:Smp_141830.1};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_141830.1};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_141830.1}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_141830.1};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3Q0KNG3; -.
DR   STRING; 6183.A0A3Q0KNG3; -.
DR   EnsemblMetazoa; Smp_141830.1; Smp_141830.1; Smp_141830.
DR   WBParaSite; Smp_141830.1; Smp_141830.1; Smp_141830.
DR   InParanoid; A0A3Q0KNG3; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   ExpressionAtlas; A0A3Q0KNG3; baseline.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 2.70.50.80; -; 1.
DR   Gene3D; 6.10.20.40; TEA/ATTS domain; 1.
DR   InterPro; IPR000818; TEA/ATTS_dom.
DR   InterPro; IPR038096; TEA/ATTS_sf.
DR   InterPro; IPR041086; YBD.
DR   PANTHER; PTHR11834:SF0; PROTEIN SCALLOPED; 1.
DR   PANTHER; PTHR11834; TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED; 1.
DR   Pfam; PF01285; TEA; 1.
DR   Pfam; PF17725; YBD; 1.
DR   PRINTS; PR00065; TEADOMAIN.
DR   SMART; SM00426; TEA; 1.
DR   PROSITE; PS51088; TEA_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          217..293
FT                   /note="TEA"
FT                   /evidence="ECO:0000259|PROSITE:PS51088"
FT   DNA_BIND        217..293
FT                   /note="TEA"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00505"
FT   REGION          22..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          169..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1104 AA;  121596 MW;  AA4B91EE7166A82F CRC64;
     MEICKGKPGF LIPNLTSATA MAAASGDGNG SSSDGDSVQM TISNNNHHHN NNNNNGNHSS
     GGNSLISLSK TISKHNMDSD LGSVKIYMNK SLSDNASAKS PHSLHLENSG ITHEHLIVES
     NHALQHHSHH HLNTQLQRSP PPLNPVLTLP SVTNTISNGS FYCNSINTNS NHQIRSGKRP
     APTTPKRLST NSADFHFDDD CVSNSGSDMD AHENSSSTDV EGVWSMDIEQ CFQEALAIYP
     PCGRRKIILS EEGKMYGRNE LIARYIYQHT GKIRSRKQVS SHIQVLARRK SKELQAQIKD
     PDTKQRAIMH LSMLSSAQIV SAGVLGSKTL PSISTSGGLP VTSSGIHPSA DDEKINEIKL
     SNSHPLNMAN NRSDMHSLIV EDIVTDRSPH INDLMHSNNR ELKNKTNGLY LENLHKYPSS
     TAVNNNVQNN YAVSNKNLIK GKSQENCSYS TVIQDDKTTQ YNHINLNPSS QSTLAHLLPI
     NSSLPQYSFD IRQQGNMVNN DSSPLSYPYE AFLALRSQQQ SNLFSRNSDT LDLHNKLLGP
     DDSKQQHEID SKQLSFPLAL DNLMTITSNN HRNQSSSPST SIVNNVNRLQ STLPTNNSSV
     VLPNLQPDGL VLVKTSVGQL IYCPSNHYNN NAIPQKIHNS TTTTINNNTD SSISSSNCSS
     ISSLSSVPSF KSTLSVPNSL GSSMISTTPS ASAAVAMAAA HVASVAAYEQ QCTTIKSVLW
     PTNPLLSSTS SPSSSHHASV LSTKSNINTF PSTVVPKHNP VLMEQLNVNH AHHNNNNNYG
     DLIANALATT NKQLSDDGTM NFLREISYSS MNLSRDSDDS ISDSPKYSRK MIVESAEKNM
     SLSNVNVTTM VTSTTPEDLT NINIPKWMGR SVTAPKMRLV ELSAYMISST SKSQSNVTPT
     HDFHLTTTPK STTTVHNFVH IGPILNEQLY TDPNLEQVDA SQIWDKFPED SLKELMEHGP
     MNTFFLVKFW ADVNVMVEPD ATFAVSAIFE GTEDVPINLS TKVCSFGKEV LEKIEDEQPR
     PENGRYVYRF LRSPMCDYMK KFIGKLLQLP QRELMNSVLE NFTILHVLTN KLTNEVLLCI
     AYVLEVAQEG CRAQHHIYRL TRYG
//