ID   A0A3Q0KPA4_SCHMA        Unreviewed;       598 AA.
AC   A0A3Q0KPA4;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Putative suppressor of potassium transport defect 3 (Skd3 protein) {ECO:0000313|WBParaSite:Smp_145990.1};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_145990.1};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_145990.1}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_145990.1};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q0KPA4; -.
DR   STRING; 6183.A0A3Q0KPA4; -.
DR   EnsemblMetazoa; Smp_145990.1; Smp_145990.1; Smp_145990.
DR   WBParaSite; Smp_145990.1; Smp_145990.1; Smp_145990.
DR   InParanoid; A0A3Q0KPA4; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   ExpressionAtlas; A0A3Q0KPA4; baseline.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF93; CASEINOLYTIC PEPTIDASE B PROTEIN HOMOLOG; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854}.
FT   REPEAT          101..133
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          170..202
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          278..450
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   598 AA;  67790 MW;  06F51D67A712BEA5 CRC64;
     MTTWVCSLRK ILFIGRKILI FSATTRYKRF ISNFAYPSSW RFTKLPLFAL AFPTIQLNTI
     GFDLNRFKNP DIFECILSMN RNSLSSILRG SKDAVKERHS LGWTPLMLAV VTKNYEAVRE
     LLKAGSNPND VDNYAGIVRT AHDLRMMSSE VEWIRLTQFS DFLNPSADFR GCSALHYAVL
     INDSKLVHLL LEFGADPTIV NERGHRPAMY AKDSSIRELL AEAESKKAEE VAAKEREERR
     LQPLENRLRK VIVGQEAAIR TVSAAIRRKE NGWYDEDHPL VFLFLGSSGI GKTELAKQVA
     AYLHKDIKKG FIRIDMSEYQ EKHEVSKFIG SPPGYVGHEE GGQLTRALAA CPNAVVLFDE
     TEKAHPDVLT ALLQLFDEGR LTDGRGTTIN CKDAIFIMTS NVGSQVIAEH AQQLRHVSGN
     DEADIEISRD FKEKVMRPIL RRHFLRDEFL GRINEMVYFL PFSTSELTEL VNRSLKSWSE
     KALKRHSLTI TWNREVVDLI VDGYDVYYGA RSINYEIERR IISLLALADE QGHLNPGSRV
     NISVSHKSVK DEAWSSKKSN ENLDPTISSP PRIVLNVTDA KGKMNKVLDL TQTTVSWA
//