ID A0A3Q0KRN3_SCHMA Unreviewed; 1050 AA.
AC A0A3Q0KRN3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Putative WD-repeat protein {ECO:0000313|WBParaSite:Smp_163210.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_163210.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_163210.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_163210.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
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DR AlphaFoldDB; A0A3Q0KRN3; -.
DR STRING; 6183.A0A3Q0KRN3; -.
DR EnsemblMetazoa; Smp_163210.1; Smp_163210.1; Smp_163210.
DR WBParaSite; Smp_163210.1; Smp_163210.1; Smp_163210.
DR InParanoid; A0A3Q0KRN3; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR CDD; cd21931; TD_EMAP-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR049813; Elp-1-like_TD.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 375..445
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 728..769
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 856..889
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1014..1050
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 50..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..283
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1050 AA; 116622 MW; B95D6A4E8C66D751 CRC64;
MNLENAGLQD RVIDLEKRSA EQANELACLR SSLADCLRRL NLLESARGMK LHSSSRKPVL
HNNGTNVTKT NSRTDSSYSS RRHTNSRNPT STGHQSKNSR DSSLVVPHST TASTTARTRL
KSPQSVRLSS SSTTLNNQGV GVSGATNQTR RNRITSASSE DRQFNNFNNN KHERDNKTLS
MYEYNDMIMS RQSEPITYQQ KSSTLKSNTS SRYYEASTGP SGYTVFWRSA YDGELDDIYR
MNHCQSPPGQ QHSVSVSSSF RKNHTVAPPP PPPPPPALPP SSLCIPPNLV RRGRQSSGPS
SSAYYCATDS DDRSVHLTST SRSLHPTAWK PGGVAICPAN REMIQSMNKP SCIPKFHDDD
SKETTYLPGD GILRFYIRGR PVNVYMPTQI MQNYDLSIPL KAPDTTLKLE WIYGYRGRDC
RNNLHYLPTG ELIYFVAAVV VLYNIEEQCQ RHYLEHTDDV KCIAIHPDRI TVATGQSAGH
DKQFGKPHVR IWSSVDLKTL KIIGLGEFER SVCCLSFSKT DSGVKLCAVD EATDHVISIW
DWQKSRKITE TKCSTEPITA VEFHPLDDAT LVSGGKGHLA FWTFDGCTLS KKMGIFENGK
QPIEKPKFIL CLTFAENGDL LTGDSAGNII AWKRGTNTVN QICQGVHEGG IFSLCLTNNG
HLISGGGKDR RLVFFDAALN PTGRTEELTE LYGSVRTITQ GPGELLIIGT TKNMILQAGP
GMEISPLMFG HFEEFWSLAK HPQAHQFITG GRDHLVILWD SLSKQAIWSK EFTDAIHCAA
FYPPQSVLIT NGTMSPVNNH NNDSNINGNN VIDETNNLDF NVSMMNSHDL LVVLGTSTGR
WLVFNCLKQE IIAAHSDGLG EQIECVAYSP DGNYLALGSR DNVIYVYNVL ERGYKYNRVG
RCCGHTSFIL HIDWSVDGRF IRSVSGDYEI LFWTAFDCRQ VVSPSTLRDL EWASQTCTLG
WEVAGIWPSD SDGTDVNACD RSPTADILAT GDDYGKVKLF KYPTNKPKAE FRAYNGHSSH
VTNVTFLYDG SRLISTGGKD TAVLQWEVCI
//
