ID   A0A3Q0KSH2_SCHMA        Unreviewed;       759 AA.
AC   A0A3Q0KSH2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Putative myelin transcription factor 1, myt1 {ECO:0000313|WBParaSite:Smp_168610.1};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_168610.1};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_168610.1}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_168610.1};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the MYT1 family.
CC       {ECO:0000256|ARBA:ARBA00010194}.
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DR   AlphaFoldDB; A0A3Q0KSH2; -.
DR   STRING; 6183.A0A3Q0KSH2; -.
DR   EnsemblMetazoa; Smp_168610.1; Smp_168610.1; Smp_168610.
DR   WBParaSite; Smp_168610.1; Smp_168610.1; Smp_168610.
DR   InParanoid; A0A3Q0KSH2; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   ExpressionAtlas; A0A3Q0KSH2; baseline.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 4.10.320.30; -; 2.
DR   InterPro; IPR002515; Znf_C2H2C.
DR   InterPro; IPR036060; Znf_C2H2C_sf.
DR   PANTHER; PTHR10816:SF15; MYELIN TRANSCRIPTION FACTOR 1-LIKE; 1.
DR   PANTHER; PTHR10816; MYELIN TRANSCRIPTION FACTOR 1-RELATED; 1.
DR   Pfam; PF01530; zf-C2HC; 2.
DR   SUPFAM; SSF103637; CCHHC domain; 2.
DR   PROSITE; PS51802; ZF_CCHHC; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          277..330
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..310
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..327
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   759 AA;  85549 MW;  6E79A0DAAF80B424 CRC64;
     MVIFVKRNNY SLFYLIFSLK LILFLFERMN NTNQLDNSVN ELTTNFEQIS PIPRTLLPID
     GRNECNPTKM CNEYHDQKKF VTPSEFIHNN NYYLINNQKN KINNNNNITD NTTHNNLVVK
     QSLLSKQNDN TKKTNHFVNY LLENNELNQN NNMNENKNDN DNLLLFDIMN TSSLNSPSSS
     ISSKSDLDNC NNNTNSNDYL TRKNFQQNIS LKIKSIQGSK KDRNTEGRCP IRDCDGTGHA
     TGLYSYHRSV SGCPRKDRAS VAELALYHQT LHCPTPGCTG RGHVNNNRSS HRSFSGCPLA
     SRNRSRQSKR PLSPQKIETR HKSNHFGVNH ESNASFSKKI HQSSSLNSKL NPCNSSLSTL
     STSSLPLSDF IKQSQPFQGI PPTDLLANFP LKNMIHTESI NSNNLVNEFS DSFSKSLYNL
     LPNLINTPQF STLFNCSTTI ANNDINMANL YHNSQTLYPM LNSSSLINNN NNDSNMKESS
     PLSNILEKST SLKPEDMNFP KCLNNASYNL NLPRCGILQD SFMYHKQYRG KHLIPTKLVD
     TDQNIINNAT SEKSNVLSQI NYRSENVSVN DNSFPINQYS LSPMIDSYTD LNKNYSISNS
     ICIENKSECP IDLSVHSKNQ LGNKDKILNT CDSVPTNKVI GRSFEIGNLC PELHESKKEV
     KNLSSTMKIM NSNNANIIAT SHPTTINSFA DMHNSKNLMS ISLSLNSNSF IDGTVSSVDV
     YSNKKHIYAN KKHSTNMGCI NLLQGRSDFE AANVLFAFN
//