ID A0A3Q0KSX7_SCHMA Unreviewed; 3457 AA.
AC A0A3Q0KSX7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 2.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ig-like domain-containing protein {ECO:0000313|WBParaSite:Smp_171680.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_171680.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_171680.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_171680.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
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DR STRING; 6183.A0A3Q0KSX7; -.
DR EnsemblMetazoa; Smp_171680.1; Smp_171680.1; Smp_171680.
DR WBParaSite; Smp_171680.1; Smp_171680.1; Smp_171680.
DR InParanoid; A0A3Q0KSX7; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 4.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF262; DPR-INTERACTING PROTEIN KAPPA, ISOFORM A; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13895; Ig_2; 1.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2881..2902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..117
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 468..558
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 562..696
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 990..1089
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2539..2650
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 3457 AA; 398736 MW; AF81CBA6569FC233 CRC64;
MVIFDERFRW IFLFCAILYV SMSGLKSFEL NDEDIPLHFT SESSYLIVAE GEQVLLPCKT
NVFSEALVSW YKDDIRIAEN LTFSFRLRSA SREDAGYYHC VVKTTYGGIR SQKVKLEIGY
LDPPSKIKAR SFIEVTLDQA VIIWPGSLDQ DKRKQPFQLE RRNGLWKSVF NPIDETNKAL
PPSYYLQAVP FPQAIWTINN APIPSTLNIF VSQLEQAIVL LNIDKEMDSK VIRARLINGY
GRANSEVFSQ THIIQVKDPP LNMATNSLDL VLPPKDVSLT LKDDQPGTAV FECVFNARPA
HALRVQWFKS TLNGKHEPIN PSNVISSSTK MSTSSNSNNN NQIIYKFDTS GLNRTLIISN
ILPSVIPSDY FQQTNQKGIY SEEYTCHAYL NDYNGNSVFD MNKFMLDDSQ FTTSVLSSPS
STNSAINLYQ RISPISTTAR LKLYLPPKVK FPPNLIMSSL TSQLEITPKY DKLVIIETSA
SMIIQLPCEL DYVGIPKAEI KWLRNGDPID THNQEYYQIH INHTLIIKNL KLTDAGIFQC
YAYNDVGEDF LNIWLKVTSF APRLCNSEII MENITVLKES TTVLTCPIHG APTPEFKWYK
ETNENEWTPI HQLYQKYKNS NYSSTIKRKQ YLIKEDDISV MSADDKLKST QRLSNSCVPM
GLNELEIYHV DYKSTGLYKC EAVNYLGNQS AFIYVSVYSR TIPVHYLPSS ITAFANQSLS
IMCSFYIDQN TIAEINWFHG RKESTLSGEK YKKHNNTMLL HETTKDNTKV ITNYNLVKSV
PIDPVITYFS RDIPQKHKPS IGLKEYGSIL HVNSVDVIHQ GFYVCEILSP GGNYTLKTEL
KVVSLPTTPT DLSVTNVFET SNYNDNNNNN IHDIGVQLLW RQPQANHQLK ITHYAIFIHK
LPNQNGLRKQ NCEIITDEEW ELFSVINLNE TIKNPTNDSY IYTIRNISII FQTGSYCFSL
SSVNFLGWSK KSNSVFYSVS NIPKTALNEI IMKLHLINVT STSIHIIWVA ALQTNKSSLS
LVKEYQLYYW IETSDFVEVK KCSNKNSFIQ QHELTNLKPL TRYHLKISAC NDYECGTFSE
VLQVQTLPHE LFKTPSLISV TVHQGNKVEI SFFSDYIDKD DYYIEQMKGY LVELSCIDPP
GCSDLQMYLP LECVMDTERF VDEHFNVNPE NTIGNQRCNE LNPLENSIFL YSANVNRSNH
QISISLNSLS PHTLYELFVA YVYTNRVGPF SRPAEVFRTI EDVPSRIINL MVNTDGRDGL
IVEWDAPEKP NGKILQYILH YTEIKPIDSL IDIHHQYDHI ESEYNTTLAF MNQRINQSSS
YDNELSIHQY PITHHLSSAY IKDSNFIHSI QTRTYDNRKY AGYYSLNRTT YRVHIKSLIH
KHIYQIRMFA LNTAGLSPVT LQLGITSLLP KLKYQYQYTE KNFIQWINLI HLNKHQEKIF
KWLNSTRIQF VSEPVITKIN AHNAEFSIEF NLKLDEDISH SIHYNQSTPV VGDFSRTIKL
IEKCKWPIKI QKIPLNGYQA LSGNDQIDSW NWRIITAYKY TINSSLKLSL TELTKFNVNQ
GVQLTLSFKL FNLSSSNYYR IEVWQPIGLL FGNYKQIASK ILYHSNLSKW FKIDCKPPTV
SPSSVSTYML NIDQMKITWQ PLSSEEWNGI PGGYLITVQE AETEHTHSSI TTYPNHDHMY
NANETVKIQI TQSKCGLDYL QIFINDSMAF SYIIGDLKLG SDYMVSIRAA SVEIGDSDKW
LLGPQTVIQH LSIYKQAKNN EDIRFLTSMR MSKFTPYNLK VSRELDWIVV SWKENIKVEC
GQLPEGYQLI FNKVWFNENT NETLPNDDDD YVNYLKFIPF NDTNLNRSKI LQSSDSFYEN
ILKLPLKIFF NPNEACYFNG YLRLQLLYII GQSVNENVEQ VTIYLNLEAE KIRHRLLLRK
VIPLSKQRKA RVLITWIPNI NNDKPLFPHT DIFTLKWTRI DPISYEKLSL PFTRLISWPD
TNNHILMNNG YAALKSAEKA SKRQKYSEYL ITVDELLMEA TYLFQLIETN FSQPINISVN
DEKMCSSKTE LLVYVTTVES FQTGPLQRPV TPKIQISHSS FTQKQYENTI CPIAKTHLSW
PNYLRQLQSN QTTEYSSGFL YTSPVTNYVL HYAEVMNNNF SEDIYSKNSN NFGSAIWKTY
QPAPQIDEVN DFLVDGLLPY KMYIFRLAAQ TDTGISPFSL PTDILITSPQ RPCSYSIKLE
FELRSHLHSE ISQRSDHTSR RRSDIVTRGY CEYLLLKWKA LNYHQWNSQP GWYHITYRLW
SSNYNNANTQ LFNLFIKHDE NQIKNSYFHV ELKNLIPNHY YLFSIEAINN YNTNNLMTSM
VQLSSSFIII HSGIGCNPIE LQYNQIKQMT RSIIMYMNKL NYPILLSKPL LSPVNFLCLS
DPIQVLIKCT WEYKEFQGIL GFILEVHEYG EINYNISHNS IQTHSIFIKP HVNGVLLHSV
SSITQSNVIL SGQTIIKPYF YYKTSIHVIT TGGHGPKAYF PQSDYKETKI NTNIKLHHST
ENGCLSGELL CTSQSPPNPP FSLASQWLSR DLIKLEWLQP EQLNGKLVNY RITWSEITFP
FKDNQFIDQN SINSKELGQQ FTMILKSFET TYTIDQLHEN TSYIFKVYAR TESKQNDGWS
IPNCIYASTS YCWFNSPQII RIISQHKCDF KTLLKTIDPS LEKFCSFNSP ILRRPVVFIS
SINKTATNPK FENLTRNSLK FHYNKTNINY ASTVITILWS EAMSGINSIT HILIELRYSW
NLNKWYSFTM INSSMRLYTF DFEDLTKLSV DLNKDSKHSF HAMRRKVKSQ TTMNEINQEA
TIRMITAAFT DANVPIDSTT HVAIQFRVSP VNQFQIGLPS QESDWSVIKL KTIATPFYHH
WWFIMMLGLC ATSIIFILLI TLKWNIHRRQ QLNKSTFVTE KSDSNVSSSN AFMNDCCLAL
KLYHSNYLTK TMNNNIQLNG EICEYPNLIN STFHNTRSPE TVELTTGIYY TENSNNMLHK
NQNPFNLALN NHNWDVLYNT SPEILIAQTD SSLGSKAPSN RTVSTSEVER FDDFTQNYNN
CITSQGLINS NQSLYPEINV PIIPSYNFSS PYSLQNNQLI TDISNSINNE ILLNQNLPSP
CNSNKLYIDQ ISAPYPYSSL QNESIMLNQN NLYKLDTNRT LKFDKSVTPF NQTINSLPSS
EYQWNTNHQN GQTHLDQKSY DVELSLTQNH SVYQKFINPI NNTSSSTINA SFNLADTILN
NHNSNQHFYQ MNANGDNYIM SKSHIGTYEP ENPNYMKYNS LQKKSLNRHS MATDYNRSER
VKTNMELNSL PMEYSPLNND NQSSVNHNGQ RLIQDFDFNL LPDHLILNGQ VNQTSISNTT
VNQISNIHPT GSHNNDVNND TVQVNENSHF TNTKHLSKQG SIHQSPSPYK NTDLLYNNYN
STMTIVKNND QDTLSNWDEN LEFHITTDLE LLTSTEV
//
