ID   A0A3Q0QSN6_AMPCI        Unreviewed;       270 AA.
AC   A0A3Q0QSN6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Aquaporin 14 {ECO:0008006|Google:ProtNLM};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000000016.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000000016.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC       {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
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DR   AlphaFoldDB; A0A3Q0QSN6; -.
DR   STRING; 61819.ENSACIP00000000016; -.
DR   Ensembl; ENSACIT00000000016.1; ENSACIP00000000016.1; ENSACIG00000000012.1.
DR   GeneTree; ENSGT00940000156037; -.
DR   OMA; ANKQENN; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015267; F:channel activity; IEA:InterPro.
DR   Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR034294; Aquaporin_transptr.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR022357; MIP_CS.
DR   PANTHER; PTHR19139; AQUAPORIN TRANSPORTER; 1.
DR   PANTHER; PTHR19139:SF177; AQUAPORIN-14; 1.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; Aquaporin-like; 1.
DR   PROSITE; PS00221; MIP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000477};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..270
FT                   /note="Aquaporin 14"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018646074"
FT   TRANSMEM        43..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   270 AA;  28678 MW;  7EC4FA7F8C800508 CRC64;
     MAELRSRQFW RAMVAELLGT LVLVSAVLGA SVPGPGEAPG GPLYPAVAVG VVIVALGHCF
     GEISGAQVNP ALTLALLATR RLDVLRALVY IIAQCLGASL GAGALYLALP FKTTADYFVN
     RVPLELNAAK ALCIEVLCTF QMVFTVFSVE DQRRRESPEP GNLAIGLAHT AGARFSGASM
     NPARSFGPAI ITGFWEDHWV YWIGPVLGAI LAGVSHEFFF ARSASRQKLV ACLTCKDIEI
     VETASMTGSS LSTVTQNATR AKQANKQENN
//