ID   A0A3Q0QSZ8_AMPCI        Unreviewed;       216 AA.
AC   A0A3Q0QSZ8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Dickkopf WNT signaling pathway inhibitor 3b {ECO:0000313|Ensembl:ENSACIP00000000186.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000000186.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000000186.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the dickkopf family.
CC       {ECO:0000256|ARBA:ARBA00010842}.
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DR   Ensembl; ENSACIT00000000192.1; ENSACIP00000000186.1; ENSACIG00000000145.1.
DR   GeneTree; ENSGT00390000000221; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:InterPro.
DR   CDD; cd23274; Dkk3_Cys2; 1.
DR   Gene3D; 2.10.80.10; Lipase, subunit A; 1.
DR   InterPro; IPR006796; Dickkopf_N.
DR   InterPro; IPR039863; DKK1-4.
DR   InterPro; IPR047300; Dkk3_Cys2.
DR   PANTHER; PTHR12113:SF8; DICKKOPF-RELATED PROTEIN 3; 1.
DR   PANTHER; PTHR12113; DICKKOPF3-LIKE 3; 1.
DR   Pfam; PF04706; Dickkopf_N; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          87..137
FT                   /note="Dickkopf N-terminal cysteine-rich"
FT                   /evidence="ECO:0000259|Pfam:PF04706"
SQ   SEQUENCE   216 AA;  24367 MW;  9F1D414B23BAEDD8 CRC64;
     SILLTHSMIT VRLHVVAKQR PTSETLERGP VSLNDMFREV EELMEDTQHI LEEAVDQVGE
     TNNKTGETHL SXVHMEISSQ WNNVNHECMV DEDCDDLKYC LYEIENSKCL PCIPTDMPCT
     KDEECCSDQM CVWGQCTVNA TEGTEGTICQ GQSDCRPHLC CAFQPELLFP VCNPKPGKGE
     SCLSHPNLLM DMLAWDQEGP RDHCPCADDL QCQPHR
//