ID   A0A3Q0QUQ4_AMPCI        Unreviewed;       252 AA.
AC   A0A3Q0QUQ4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Claudin 34 {ECO:0008006|Google:ProtNLM};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000001195.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000001195.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}.
CC   -!- SIMILARITY: Belongs to the claudin family.
CC       {ECO:0000256|ARBA:ARBA00008295}.
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DR   AlphaFoldDB; A0A3Q0QUQ4; -.
DR   STRING; 61819.ENSACIP00000001195; -.
DR   Ensembl; ENSACIT00000001247.1; ENSACIP00000001195.1; ENSACIG00000001016.1.
DR   GeneTree; ENSGT00390000005717; -.
DR   OMA; HWQFLGL; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR006187; Claudin.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   PANTHER; PTHR12002; CLAUDIN; 1.
DR   PANTHER; PTHR12002:SF4; CLAUDIN-34; 1.
DR   Pfam; PF13903; Claudin_2; 1.
DR   PRINTS; PR01077; CLAUDIN.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   252 AA;  27930 MW;  02A40BCFFFB12A0B CRC64;
     MKSYREWFCF TFLGLIVGFL AWILTMTTVG LNEWRLWQVA NVSVITSGEA WVGIWRVCFY
     SHDVPGMENC QSISISDIFA PVEIAVAQVL MMLAVIFGLA GNISGAVALR MVYFSVEDRR
     NIRLVFLLAG VLYLLSATSS LVPLVWNMSS VLKNSTIDFP PEFQIPAPPV SQRIGSTIGV
     GLCTSIAMFV SGLLFLCYRY AWRAVSTEGP RDPLDGPRDP LDGPWTLTTL PHKSELSNRV
     GNGIDNASFH RE
//