ID A0A3Q0QW79_AMPCI Unreviewed; 542 AA.
AC A0A3Q0QW79;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Inositol polyphosphate-5-phosphatase Jb {ECO:0000313|Ensembl:ENSACIP00000001546.1};
GN Name=INPP5J {ECO:0000313|Ensembl:ENSACIP00000001546.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000001546.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000001546.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR AlphaFoldDB; A0A3Q0QW79; -.
DR STRING; 61819.ENSACIP00000001546; -.
DR Ensembl; ENSACIT00000001614.1; ENSACIP00000001546.1; ENSACIG00000001231.1.
DR GeneTree; ENSGT00940000156855; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR CDD; cd09094; INPP5c_INPP5J-like; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF127; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A; 1.
DR Pfam; PF17751; SKICH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 12..330
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT REGION 435..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..464
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..481
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 542 AA; 60438 MW; 1338B646EFCCAAC6 CRC64;
MSVCKGYYIT PFSNRVHVIT WNVGSATPPD DITSLLGLNV GDGNTDMYII GLQEVNSMIN
KRLKDALFTD QWSEVCMERL SPFGYVLVTS QRMQGVLLLI FAKYFHLPFL RGVQTETTRT
GLGGYWGNKG GVSARMSVYG HTICFLNCHL PAHMENSDQR MEDFESILQQ QQFEGQASTG
VLDHDVVFWF GDLNFRIDEL EMQVVKSAID NNKFSILWEK DQLNMAKDSE TVLEGFQEGP
LKFPPTYKFD VGTNTYDTSG KKRKPAWTDR ILWRLRATAP VGAGKRGSIS GLTSGTKVTQ
HSYRSHMEFM ISDHKPVSSI FTLQFPYKVD IPLVTIIVED EWNSVADATP IFKLAPNYSR
SSWDWIGLYK VGFKHYKDYV GYVWAKQEES DFLRQEHQVT FTEEELPKGS GDFILGYYSN
NMSSIVGVTE PFQIQLPTTG DDTSSSDSSD FTSEDDSTVV MKMRSRSPSP RKAKHRGRRS
GSQSCSRSGS PPQAKMKGLD ITDGPPSSAT AESESPGAPT EGSSSQLSGP EAQAKNSQDP
GV
//
