ID A0A3Q0R0T6_AMPCI Unreviewed; 641 AA.
AC A0A3Q0R0T6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=1,4-alpha-glucan branching enzyme {ECO:0000256|ARBA:ARBA00012541};
DE EC=2.4.1.18 {ECO:0000256|ARBA:ARBA00012541};
GN Name=GBE1 {ECO:0000313|Ensembl:ENSACIP00000003708.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000003708.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000003708.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan chain to a
CC primary hydroxy group in a similar glucan chain.; EC=2.4.1.18;
CC Evidence={ECO:0000256|ARBA:ARBA00000826};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family. GlgB
CC subfamily. {ECO:0000256|ARBA:ARBA00009000}.
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DR AlphaFoldDB; A0A3Q0R0T6; -.
DR STRING; 61819.ENSACIP00000003708; -.
DR Ensembl; ENSACIT00000003830.1; ENSACIP00000003708.1; ENSACIG00000002849.1.
DR GeneTree; ENSGT00390000017040; -.
DR OMA; YEMHLGS; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0003844; F:1,4-alpha-glucan branching enzyme activity; IEA:UniProtKB-EC.
DR GO; GO:0102752; F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis); IEA:UniProtKB-EC.
DR GO; GO:0043169; F:cation binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
DR CDD; cd11321; AmyAc_bac_euk_BE; 1.
DR CDD; cd02854; E_set_GBE_euk_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR006048; A-amylase/branching_C.
DR InterPro; IPR037439; Branching_enzy.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR004193; Glyco_hydro_13_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR43651; 1,4-ALPHA-GLUCAN-BRANCHING ENZYME; 1.
DR PANTHER; PTHR43651:SF3; 1,4-ALPHA-GLUCAN-BRANCHING ENZYME; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF02806; Alpha-amylase_C; 1.
DR Pfam; PF02922; CBM_48; 1.
DR PIRSF; PIRSF000463; GlgB; 2.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 151..501
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 641 AA; 73827 MW; D1147D384F06B018 CRC64;
RNLSEINCKV VSLSFLEEAE GGFDQFTRSY NTFGVQRRPD NSLYLREWAP AAEALFLTGD
FNGWDKFSHP YTKKEFGKWE LILPPKHDKS PAVDHNSKLK VVVHTKEGQR LYRISPWAKY
VTREEKSVIY DWVHWDPPQP YIVIHPRPRK PASLRIYEAH VGIASPEGKI ASYSNFTTNV
LPRIKDLGYN CIQLMAIMEH AYYASFGYQI TSFFAASSRY GTPDELKQLI DVAHSMGIMV
LLDVVHSHAS KNTEDGLNRF DGSDSCFFHS PPRGEHSMWG SRLFNYSRFA LILHGTGFTG
DYSEYFGLQV DEDSLVYLML ANHILHALYP DCITVAEDVS GMPALCRKVE EGGLGFDYRL
AMAIPDKWIQ ILKELKDEDW NMGDIIYTLT NRRYGENCIA YAESHDQALV GDKSLAFWLM
DKEMYTNMSS MIPMTHIIDR GMQLHKMIRL ITHGLGGEGY LNFMGNEFGH PEWLDFPREG
NNQSYHYARR QFNLVDMDHL RYRQLYAFDR DMNRTEDKYG WLVAPPAFVS AKHEEDKVIV
FDRANVLFIF NFHPSKSFQD YKVAVEVPGK YKIKLDSDAA QYGGHGRLDP NTEFFTQPEP
FNGRSNSIQV NTCGITFSDL YLISRSVDLP VDLHPYPHLW S
//
