ID   A0A3Q0R7V6_AMPCI        Unreviewed;       561 AA.
AC   A0A3Q0R7V6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Lactase {ECO:0000313|Ensembl:ENSACIP00000005963.1};
GN   Name=LCT {ECO:0000313|Ensembl:ENSACIP00000005963.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000005963.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000005963.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC       {ECO:0000256|RuleBase:RU003690}.
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DR   Ensembl; ENSACIT00000006143.1; ENSACIP00000005963.1; ENSACIG00000004503.1.
DR   GeneTree; ENSGT00940000155324; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU004468};
KW   Hydrolase {ECO:0000256|RuleBase:RU004468}.
FT   ACT_SITE        413
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   561 AA;  64792 MW;  5374D4634F8ECAC8 CRC64;
     MKLTQRSAAL PPSEVPSKSK VVWEKFSSQS QFHRQMYHYG TFPQGFSWGV SSSAYQIEGG
     WNADGKGXSX WDTFTQTPGN IPDNANGNVA CDSYXRLNED LYMLRALRVK SYRFSLSWSR
     IFPDGTRSXL NQKGVDYYNR LIBGLVAYNI TPMVTLYHWD LPQALQKLNG WENVDMIEIF
     NDFCDFCFAT FGDRVKFWMT FNQPQTIAWS GYGLGNMPPN VKDPGYXPYR VAHNLIKAHA
     KAYHTYDDKY RKSQGGLISI ALNSNWFEPV DVNVVREMVA ADRAMQFQLG WFAHPIFKNG
     DYPEALKWQV GNKSEIQGLS ESRLPSFTEA EKSFIKGTAD VFCINHYTTS VVSHFTAALQ
     PHSYEWDRDL RETEHTDSPT TAIPNQKAVA WGLRRLLNWI KEEYGDPEIY VTENGAAVEW
     DDFERVMFYK TYIDEALKAY ELDGVRVRGY TATSFMDSFE WLHGYRFLFG MHHVDFTNPD
     RPRTPKYSAH FYYNVIKDNG FPMPDDEKML YGHFREDFMW STASSAYQAP SLLQVLNDQT
     ILVLLTFSYI VCLMSFRVNI A
//