ID   A0A3Q0R894_AMPCI        Unreviewed;       698 AA.
AC   A0A3Q0R894;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Adenosine deaminase RNA specific B1b {ECO:0000313|Ensembl:ENSACIP00000006267.1};
GN   Name=ADARB1 {ECO:0000313|Ensembl:ENSACIP00000006267.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000006267.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000006267.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   STRING; 61819.ENSACIP00000006267; -.
DR   Ensembl; ENSACIT00000006453.1; ENSACIP00000006267.1; ENSACIG00000004927.1.
DR   GeneTree; ENSGT00940000155992; -.
DR   OMA; FCMNVSK; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd19895; DSRM_RED1_rpt1; 1.
DR   CDD; cd19898; DSRM_RED1_rpt2; 1.
DR   Gene3D; 3.30.160.20; -; 2.
DR   InterPro; IPR002466; A_deamin.
DR   InterPro; IPR044458; ADAR2_DSRM_1.
DR   InterPro; IPR044459; ADAR2_DSRM_2.
DR   InterPro; IPR014720; dsRBD_dom.
DR   PANTHER; PTHR10910:SF58; DOUBLE-STRANDED RNA-SPECIFIC EDITASE 1; 1.
DR   PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR   Pfam; PF02137; A_deamin; 1.
DR   Pfam; PF00035; dsrm; 2.
DR   SMART; SM00552; ADEAMc; 1.
DR   SMART; SM00358; DSRM; 2.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR   PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR   PROSITE; PS50137; DS_RBD; 2.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN          75..141
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          226..295
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          367..694
FT                   /note="A to I editase"
FT                   /evidence="ECO:0000259|PROSITE:PS50141"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          198..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..226
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   698 AA;  76869 MW;  0A1491A944078288 CRC64;
     MDVDEEENMS SSSTDVKENR NLDNVSCKDG VGVAEQLPNG SGLGSRKRPL EEGNNGHTHS
     KFRAKKRKKT PGPVLPKNAL MQLNEIKPGL QYKLLSQTGP VHAPVFVMTV EVNGQMFEGM
     GPTKKKAKLN AAEKALRSFV QFPNASEAHL AMGRTLTVNT DFTSDQADFP DMLFNGFETP
     AAPEESFYLG SNGSSSLNSL GEYPLPTPTG SNLVQPPLPP PSAFSSPSSG KNPVMILNEL
     RPGLKYDFVS ESGESHAKNF VMSVTVDSQT FEGSGRNKKL AKARAAQAAL SALFNMQLDQ
     TPSRQPIPRE GLQLHLPQVL ADAVSRLVVD KFSELTDNFT SPHARRKVLA GVVMTTGTDV
     KEAQVICVST GTKCINGEYM SDRGLALNDC HAEIIARRSL IRYLYTQLEF FLSNIKEDHQ
     KSIFVPCDKG GYRLEDNVQF HLYISTSPCG DARIFSPHEA GVEDQGDRHP NRKARGQLRT
     KIESGEGTIP VRSSNTIQTW DGVLQGERLL TMSCSDKIAR WNVVGIQGSL MSYFTEPIYF
     SSIILGSLYH ADHLSRAMYQ RIADIEDLPQ QFTLNRPLLS GISNAEARQP GKAPNFSVNW
     TVGDQALEVI NATTGKDDMG RASRLCKHTL YXRWVRLHSK LSSILRIKMS KPSSYHEAKQ
     AATEYHSAKQ ALIKAFHKAG LGAWVKKPIE QDQFTLSS
//