ID A0A3Q0R8D5_AMPCI Unreviewed; 663 AA.
AC A0A3Q0R8D5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Stabilin 2 {ECO:0000313|Ensembl:ENSACIP00000006133.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000006133.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000006133.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR Ensembl; ENSACIT00000006315.1; ENSACIP00000006133.1; ENSACIG00000004189.1.
DR GeneTree; ENSGT00940000156566; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.30.180.10; FAS1 domain; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR036378; FAS1_dom_sf.
DR InterPro; IPR000782; FAS1_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR000538; Link_dom.
DR PANTHER; PTHR24038; STABILIN; 1.
DR PANTHER; PTHR24038:SF0; STABILIN-2; 1.
DR Pfam; PF12947; EGF_3; 2.
DR Pfam; PF02469; Fasciclin; 1.
DR Pfam; PF00193; Xlink; 1.
DR PRINTS; PR01265; LINKMODULE.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00445; LINK; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF82153; FAS1 domain; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS50213; FAS1; 1.
DR PROSITE; PS01241; LINK_1; 1.
DR PROSITE; PS50963; LINK_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 569..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..143
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 150..187
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 191..229
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 232..274
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 307..400
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 420..554
FT /note="FAS1"
FT /evidence="ECO:0000259|PROSITE:PS50213"
FT DISULFID 133..142
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 177..186
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 329..398
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
FT DISULFID 353..374
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
SQ SEQUENCE 663 AA; 71828 MW; 7967D4E392055FCD CRC64;
LIKNDCQNIP LIITQTAQNG VSILNWWKTV RHSMQLGLSP SFIKHSECVA LSFAANISVL
FCVQEVQKCD LPTIHFAKNT GCRPVCTITI WQPKCCRGYY GRDCLVCPGG VGSLCNNRGK
CDDGHLGNGT CTCDAGFRGT ACELCSDGFY GPTCKACNCS ERGSCDDGWR GTGLCFCEAG
WTGDRCDIQL TDDVCQIWNG GCAKGAKCSQ KGGKVSCTCP KGHTGDGFTC LPIDPCASGD
NGGCHEHATC TMTAPGRRKC SCKDNYIGDG VTCEVKQLPI SRCLQDNGQC HLDAKCTDLH
FEDAMLGVFH YRSKKGQYKL NYTAAQQACA AEEGCLATYT QLAYAQQGGL NMCAAGWLDQ
ARVAYPTTYS NPNCGFGHVG IVDYGIRKNL SETWDTFCYR LKEVKCECKA GYVGDGFSCT
GNLLQVLRST PTFSNFLTQI LNCSLASESG KQFVQRLSNL TVQSTLFVPD NSGLPGNQTL
SLRDIEFHLS EGRAFPLSQL KNGSRIRTRV GSLTVLGVAD QLNPSSSRYI NDRFVTDSDI
LAANGIIHVL QAPLKAPSPH PQMHAAHKAG MGIGVVLLMA LMGGAXFVGY RFYSHSTKPF
QFHYFKEDDG EEEAPPANCS RSICNPVYEA APEAAESGEP AVTVSQQHVV GMKHLKQQLQ
LQH
//
