ID A0A3Q0RIP1_AMPCI Unreviewed; 384 AA.
AC A0A3Q0RIP1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Inhibin subunit beta Aa {ECO:0000313|Ensembl:ENSACIP00000012104.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000012104.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000012104.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3Q0RIP1; -.
DR Ensembl; ENSACIT00000012446.1; ENSACIP00000012104.1; ENSACIG00000009351.1.
DR GeneTree; ENSGT00940000157116; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19404; TGF_beta_INHBA; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF293; ACTIVIN BETA A SUBUNIT; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 265..384
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 12..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 384 AA; 42431 MW; E91B4B8B0A3ACE6A CRC64;
DTLMHAVHAA EPLLGHSASG ENEGVAAGDA MAGHDQDEED AAQQDVVEAV KRHILNMLHL
QARPNITRPV PRAALLNALR KLHVGRVAED GSVQIEGEEE ETTEIITFAE PGEAPGTVNF
VLSKEGGDLS LVEQANVWLF LRLAKTNRSR AKVTIRLFQQ HHPSSGHSSL PQDDILLAEK
TVDTRRSGWH TFPVSGAVQA LLQSTTSSTL SLRVSCPLCA DTGATIVLVS GSSETLQRSN
QREQSHRPFL MAVVRQGDGS DSQRRRKRGL ECDGKVRVCC KRQFYVDFKD IGWNDWIIAP
RGYHANYCEG ECPSHVASIT GSTLSFHSTV ISHYRMRGYS PFQNVKSCCV PTRLRAMSML
YYNEEQKIIK KDVQNMIVEE CGCS
//
