ID A0A3Q0RMI4_AMPCI Unreviewed; 623 AA.
AC A0A3Q0RMI4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Xenotropic and polytropic retrovirus receptor 1a {ECO:0008006|Google:ProtNLM};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000009880.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000009880.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR AlphaFoldDB; A0A3Q0RMI4; -.
DR STRING; 61819.ENSACIP00000009880; -.
DR Ensembl; ENSACIT00000010169.1; ENSACIP00000009880.1; ENSACIG00000007715.1.
DR GeneTree; ENSGT00940000164519; -.
DR OMA; IGVMFAH; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14477; SPX_XPR1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF132; SI:DKEY-6N6.7 PROTEIN; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 2.
DR Pfam; PF03105; SPX; 3.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 236..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..176
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 362..570
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 576..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 70..97
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 609..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 73274 MW; ED137D9EB116A77A CRC64;
MKFAEHLSSH ITPEWRKQYL QYEAFKDMLY AAQDQAPSVE VTDEDTVKRY YAKFEERFFQ
TCEKELLKIN TFYSEKLAEA QRRFATLQNE LQSSLDAQRE SNAPPSLRKR KTRFHLSQEE
RCKHHNIKDL KLAFSEFYLS LILLQNYQNL NFTGFRKILK KHDKILDTSR GADWRVAHVE
VAPFYTCKKI TQLITETETL VTSELEGGDR QKAMKRLRVP PLGAAQPALA WTTFRVGLYC
GFFIILVVCA VFFRSENVWP MVRIYRGGFL LIQFLFLLGI NTYGWRQAGV NHVLIFEINP
RNNLSHQHLF EIAGFLGVLW CLSILSCLYS QYTYIPMQAN PLILYGFILL FLINPFKTCY
YKSRFWLLKL LFRVFTAPFH RVEFADFWLA DQLNSLVFVL MDLEYLFCFY IFELQWSNSK
GLLPDFREQN HADADTFFYL LIVFSIVSSL YTLIWDLRMD WGLFDRGAGE NIFLREEIVY
PHKAYYYCAI VEDVILRFAW TIQISLTTMT KIHSTGDIVA TVLAPLEVFR RFVWNFFRLE
NEHLNNCGEF RAVRDISVAP LNADDQTLLE QMMDQEDGVR NRSGKKTWKR SHSLSLRRPL
LSSSQSKKDT KVLIEDTDDE AFS
//
