ID   A0A3Q0RMS7_AMPCI        Unreviewed;      1113 AA.
AC   A0A3Q0RMS7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 2 {ECO:0000313|Ensembl:ENSACIP00000013619.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000013619.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000013619.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q0RMS7; -.
DR   Ensembl; ENSACIT00000013988.1; ENSACIP00000013619.1; ENSACIG00000010493.1.
DR   GeneTree; ENSGT00940000160123; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 3.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR040849; MyBP-C_THB.
DR   PANTHER; PTHR13817:SF187; IMMUNOGLOBULIN-LIKE AND FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR13817; TITIN; 1.
DR   Pfam; PF00041; fn3; 3.
DR   Pfam; PF07679; I-set; 6.
DR   Pfam; PF18362; THB; 1.
DR   PRINTS; PR00014; FNTYPEIII.
DR   SMART; SM00060; FN3; 3.
DR   SMART; SM00409; IG; 7.
DR   SMART; SM00408; IGc2; 4.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
DR   SUPFAM; SSF48726; Immunoglobulin; 6.
DR   PROSITE; PS50853; FN3; 3.
DR   PROSITE; PS50835; IG_LIKE; 5.
PE   4: Predicted;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          44..134
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          317..404
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          431..519
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          621..718
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          721..817
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          821..911
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          916..1010
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          1019..1107
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   1113 AA;  125067 MW;  34CA6392D1118AA4 CRC64;
     CRKKKKKLLS YQAWIMVAIK KRSRVPGVMI TQTVEQLPPG KSTPDFTRKP MPATVQEGKK
     AFFKAMVSGE PAPTVTWGRN KGEIDDPEKY KTRYDERARE HILEIIDVKP DQKDTYKCFA
     TNEYGKAVCT TTLNVISTSN YLKCVLCAVM TSDAPFLSVV VTRKKQLPPK KEGEIDPKLW
     ELLICAPRKD YEKICLEFGV TDFRWLLKRL NQMKKEREDE QAKVVETLDN VKQIEVKPYG
     RAEFGFDMQL WDPNSAINLY KDGVMVPYCD DENSKHSLKK TETNYTFSIK DPQPEDAGFY
     QVDVEEANVL TTEFRVPAVE FVDKIKDVKA VESEDAVFQC VLSTPLNRIT WSREDSSLEH
     GDKYEITVSE DKLTHTLRVK DCEITDKGAY YAIAGIASSR ASLVVEGETF FLCCIHTGST
     IKNKNSNCVV PRETLLNFVC GLSDMNANMG EQVELSCKLS SESSEGRWYK NGKPLTNQDG
     VTIIKDGACH RLIIDCCNKD DAAVYRFEAE GRKSEATLNP PKMDPDALGK FTKPVIIKAG
     ENAQWKLPFS GGAPMTIHWY KDDDELLPAL NVKIETSDSE SQLRLIKCQR KDSGEVKIKI
     KNEFGTTEAI SNLIVLDKPT PPQGPVDIME SAVTSVEFKW KPPKDSGGCP ITNYIIERQQ
     VGRNKWSNLG EIPGNSPSYK DSDVDPGRRY CYRIRAKTAE GISDYLQTED IPAGVLRYPG
     PPAVPKVVST SKDCINLSWG PPCDTGGTKI VGYNLEKNKK GTNYWSLVNQ KGPITDTKYA
     VKDVFEGAAY EFRVSAVNLS GAGDPSIPCE TVIARDPMIK PKFKDRNMKT FVVVKSGNTV
     RLNISFEASP LPEISWLKDG IPVPKHVTIT NSDKGSQLLI PTSERSDTGI YTIIVKNIVG
     QESFNVEIRV TDDPKPPGPV ELEQNIPGTV TLRWTPSPDE KRDDRLHYMV SKRDSFKRTW
     RTAADNLFNN KFTVVNILPG REYYFRVFAK NDMGLSPPAE SPFKVNRPEI KRLNFESSPS
     FIVPLKRRTA PQGYECYMSC AVKGDPAPRV TWYWNNMSLN TNTNYHITNV CGVCSLLILR
     VGPKDNGEYK VIIENKLGTA ESSMTLNVRG IYV
//