ID A0A3Q0RQI3_AMPCI Unreviewed; 618 AA.
AC A0A3Q0RQI3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000010880.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000010880.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A3Q0RQI3; -.
DR Ensembl; ENSACIT00000011197.1; ENSACIP00000010880.1; ENSACIG00000007486.1.
DR GeneTree; ENSGT00940000164201; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 30..304
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 532..618
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 618 AA; 70000 MW; 1BD13044E7CD6DFB CRC64;
MSTLNQQYEE KVRPCIDLID SLRSLGVEKD LALPAIAVIG DQSSGKSSVL EALSGVALPR
GSGIVTRCPL ELKMKRKKEG EDWSGKISYP GHEEEKIGDP TSVGEKIEEA QNEMAGVGVG
ISDELISLEI ASPDVPDLTL IDLPGIARVA VKGQPENIGD QIKRLIQRFI KKQETISLVV
VPCNVDIATT EALKMAQQVD PEGERTLGIL TKPDLVDKGT EQTVVEIVHN EIIPLKKGYM
IVRCRGQKEI TEKVSLNEAL ETEEVFFKDH AYFHTLYSEG HATVPKLAEK LTLELVHHIE
KSLPRLEEQI DEKLAQTQAE LDRYGNGPPS DPAQRLIFLI DVSSLTLCNI YVATLKVTAF
TQDRTSIMTL IYTIWFAVNK KIEKEMDSYE EKYRGRELPG FINYKTFEVM VKEQIKQLEE
PAVKKLKDIA DAIKKVFLQL AQRNFTGFPN LIKTAKAKIE AIKQQKEATA ESMLRTQFKM
ELLVYSQDRT YSSSLSESKK EEDEEQEKHG YKVKLSIPEI SRVFTKDNHA TLLELTLHLK
SYYRIAGQRL ADQIPLVIRY HMLQESAIQL QREMLQMLQD KENLEFLLKE DSDIGSQRAT
LQSRHTRLMK ARGYLVEF
//
