ID   A0A3Q0RUP0_AMPCI        Unreviewed;       418 AA.
AC   A0A3Q0RUP0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSACIP00000014431.1};
GN   Name=TMEM145 {ECO:0000313|Ensembl:ENSACIP00000014431.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000014431.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000014431.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q0RUP0; -.
DR   STRING; 61819.ENSACIP00000014431; -.
DR   Ensembl; ENSACIT00000014816.1; ENSACIP00000014431.1; ENSACIG00000011226.1.
DR   GeneTree; ENSGT00940000153981; -.
DR   OMA; WFLCHPL; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR   InterPro; IPR047831; GPR180/TMEM145.
DR   InterPro; IPR019336; GPR180/TMEM145_TM.
DR   PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR23252:SF24; TRANSMEMBRANE PROTEIN 145; 1.
DR   Pfam; PF10192; GpcrRhopsn4; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        115..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        182..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        258..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        288..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          84..338
FT                   /note="GPR180/TMEM145 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF10192"
SQ   SEQUENCE   418 AA;  47876 MW;  4A0F0BA59DF463D2 CRC64;
     EFGRLDFWFR YPKSRCCQNI LLYFDDSSQW PAVYKRPEKN CYQKEAVLRP ENNQVINLTT
     LYTWSGCVVL RCKGGRSFRS GDGLQLEYEM TLTNGKSFWT QHFSADEFGI LETDITFLII
     FSMVFLLSCY FACKYCLFGL LLCLSFNVFI FQSPLKLLSL LFHCVYWGLY ARDGVGNGSL
     KILGKLLFSV SFLVFLLMLI LLGKGFTVTR ARISHSGSVK LSIYMTVYTI TYVILFIYEA
     EFFDPGEVLY AYDSPAGYGL MGLQLVAYVW FCYAVLVSLK HYPEKQPFYV PFFTTYTLWF
     FAVPVMALIA NFGIPRWARE KIVNGIQLGI HLYAHIVFLV ITRPSAANKN FPYHVRTSQI
     GILLSSPKGG EGAESFPHHA YGNSSFLGDS QPNFTELFSI QSVSLNCMCV YIYVHLDY
//