ID   A0A3Q0RYK4_AMPCI        Unreviewed;       297 AA.
AC   A0A3Q0RYK4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Si:ch211-87j1.4 {ECO:0000313|Ensembl:ENSACIP00000015537.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000015537.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000015537.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TMEM178 family.
CC       {ECO:0000256|ARBA:ARBA00008199}.
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DR   AlphaFoldDB; A0A3Q0RYK4; -.
DR   Ensembl; ENSACIT00000015949.1; ENSACIP00000015537.1; ENSACIG00000012074.1.
DR   GeneTree; ENSGT00390000015299; -.
DR   OMA; CKHNELM; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   InterPro; IPR039625; T178A/B.
DR   PANTHER; PTHR32005:SF3; TRANSMEMBRANE PROTEIN 178B-LIKE; 1.
DR   PANTHER; PTHR32005; TRANSMEMBRANE PROTEIN 178B-RELATED; 1.
DR   Pfam; PF13903; Claudin_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..297
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018525946"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   297 AA;  33443 MW;  B73C99C6E83CAFE8 CRC64;
     MRTLTVAGLF LAFCALGLIA VAISTDNWYE TDARRHRERC KNYSNKRNDP GYIYISNTNL
     PLRMLPKEKN VERKGSSVSG EILPRAKRHF LPPAPAMESL CSRHFNSTVT GLWRKCHREG
     FDLETEDLIF KGLVPRCTPI KYYYSSSELP RNLPINLTKT IRQDEWHALH LQRMTASFIG
     MAISIILFGW IIGALGCCQD HDLMQYVAGL LFLMGGTCCI ISLCTCVAGI NFELSRYPRY
     MFGIPEDISH GYGWSMFCAW GGLGLTLLAG FLCTLAPSLY PPQTSSVHKP RQENGCV
//