ID   A0A3Q0RZD5_AMPCI        Unreviewed;      1115 AA.
AC   A0A3Q0RZD5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000013675.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000013675.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   STRING; 61819.ENSACIP00000013675; -.
DR   Ensembl; ENSACIT00000014044.1; ENSACIP00000013675.1; ENSACIG00000010616.1.
DR   GeneTree; ENSGT01100000263513; -.
DR   OMA; SGKDQAC; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 8.
DR   SUPFAM; SSF52047; RNI-like; 2.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          255..389
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   1115 AA;  126628 MW;  3E1D40FD0903E761 CRC64;
     MPESLETVFL CRQEHFSQSG CFLHRLHQEI PEVYGGASDV EHQIDMQSIF KVDLSQCAPN
     TVTTVFTLFL GSFCFFFFFF FSFFYLQVYI ETFHINFQLL EESIFTFVKD ELKRMQRLLK
     SECSDEEIDT DVDESMRSSK EAFLKIALNF LRKIKQEDLA NSLQKSPVLC QHKLKSSLKR
     KFQCLFEGAA KTQSPTFLNE IYTELYITEG GTGEVSNEHE VRQIETTARK PVRPERTITC
     EDIFKASPGR DEPIRTVLTK GVAGIGKTVL TQKFTLDWAE DKANQDIQFM FPFTFRELNL
     LKASKFSLVK LIHQFFPETK EAGICXFEDF QVVFIFDGLD ECRLPLDFHN TEILTDVTES
     TSVDVLLTNX IRGNLLPSTR LWITTRPAAA NQIPPQCVDM VTEVRGFTDP QKEEYFRKRF
     GEEQEASRII SHIKTSRSLH IMCHIPVFCW ITATVLEDVL KTRAGGELPK TLTEMYIHFL
     VVQAKLWSVK YHLGAETDPH WNPGSREMVL SLGKLAFEQL QKGNLIFYES DLTECGIDVR
     VASVYSGVFT QIFKEERGLH QEVVFCFVHL SVQEFLAALY VFLTLTNSGV NLLQPKTXWL
     NLFRDKSKLS YLFQSAVEMA VQSPNGHLDL FLRFLLGLSL PXNLTLLGGL MTXTXNILHA
     NQETIEYIKT VVRRNLTAER SINLFHCLNE LNDRSLIEEI QQYLNSGSLS TBKLSPAQWS
     ALVFILLSSE EDLDVFNLKK YSASDEGLLR LLPVVKASNK SLLSGCNLTE RSCEGLASVL
     SSHTSHLREL DLSYNDLQDS GLKQLSAGLK SPNCRLETLR SGYCFLHSNY ELYCFLKFFF
     SLIGCNLSEK SCDTLSSILN CYTLSELNLS VNNLKDSGVT IFSEQRNQHC RLETLRLSRT
     GLTEKCCQEL SSALRTESSS LRVLDLSDND LQNSGVKFLC EGLASPHCQL QTLRCHLCSK
     FKYVKFFCKG TFCENPLQNL MKTFTTRLNQ TNLTEECCTE ISTVLSSQSS RLRDLDLSNN
     DLQDSGVTLL SAGLHSPYCI LETLRLSGCS ITADGCTSLA SALRSNPSYL KELDLSYNHP
     GESGEKLLSA GLKDPHWTLE ALRYDVQRSF TLQEH
//