ID   A0A3Q0S039_AMPCI        Unreviewed;      1214 AA.
AC   A0A3Q0S039;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000018199.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000018199.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q0S039; -.
DR   STRING; 61819.ENSACIP00000018199; -.
DR   Ensembl; ENSACIT00000018688.1; ENSACIP00000018199.1; ENSACIG00000014155.1.
DR   GeneTree; ENSGT00940000167495; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 10.
DR   Gene3D; 2.60.40.60; Cadherins; 12.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF290; PROTOCADHERIN1-ALPHA-AV15-VCP-RELATED; 1.
DR   Pfam; PF00028; Cadherin; 6.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 9.
DR   SUPFAM; SSF49313; Cadherin-like; 11.
DR   PROSITE; PS00232; CADHERIN_1; 5.
DR   PROSITE; PS50268; CADHERIN_2; 10.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          54..126
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          127..234
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          235..340
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          341..437
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          438..546
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          547..654
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          655..760
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          761..920
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          921..1029
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          1030..1137
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   1214 AA;  132783 MW;  36F02C8BDB67B126 CRC64;
     LGNFSVTFCH IFHTFQLLFL LGLGNILKYV DMTPCAPMLS LSLFSDGQFS VQQYKLSSND
     NFRLEVKEKR DDVKIPILVV QKSLDRETAR SHSLILTALD GGKPPKSGNM SILLNVLDIN
     DNAPVFSKDV YSVTLNENVP VGTTIIQVNA TDLDDGTNGD VVYSFSNSMN QNIFNLIDIN
     PLTGELTVKG LIDYEEQDGY EIEIRASDKG FAPLTTEKSI NIKIVDVNDN APEIEVTSFS
     SSIPEDSRPG ITVALISVND LDSGLNGKVI CTINEDVPFN LSPSLKDKMF SLVTKSPLDR
     EKQSQYELTI TAKDAGHPAL SSEKTISVVV SDVNDNSPEF SLSPYTFYLT EGNVPGASVF
     SVKASDNDEN DNLRHFFFFF LVSRHGKHVY YNSLSCSEKV DRVVSCLINL KTVLENPLEV
     HYVGVEVLDI NDHSPSFPEK EKTLEISESV LPGVRIPLQP ARDPDGGPFT IQQYKLGSND
     HFRLEVKDKG EDGKIPILIV QQSLDREAAG SHSLVLTALD GGKPVKSGEM TILINVLDIN
     DNAPVFSEDV YSVTLDENAP VGTIIVHVNA TDLDDGPNGD VVYSFSSIVN SRLLKLFDIN
     PTTGEITVKS HIDYEEKDKY EIEIQASDKG LAPLSTQKSV IVKIVDVNDN APEIEVTSFS
     SSIPEDSRPG TTVALISVND LDSGLNGKVI CSIGKDVPFT LSPSLQDKMF SLVTKSPLDR
     EKMVKYELTI TAKDAGQPPL SSEKTISIVV SDVNDNSPEF SLSPYTFYVT EGNVPGASVF
     SVKASDNDEN DNEKGIGKGC VASGFVVMFL WSLASAQLRY SISEETNEGT VVGNIAKDLG
     LDKRTLKARK YRIVSSSAEP LFHVNQNDGN LYVSRKIDRE EVCAQSSTCV INVKTVLENP
     LEVHYVGVDV VDINDHSPVF PEDEKMLEIS ESVLPGARFQ LKPSRDLDSG QFSVQQYKLN
     HNEHFRLEVR DKGDDGKIPI LVLQKALDRE AARSHSLVLT ALDGGKPPKS GNMNILVNVL
     DVNDNTAIFS KDLYSVMLYE NAPVGTEVIQ VNATDLDDGQ NGEVVYSFGN SVSNNLFNLF
     GIDQSTGKIT VKGLIDYEQK DKYEIEIQAS DKSFAPLTTE NSVIIEIVDV NDNAPEIELT
     SFSSSIPEDS RTGTTVALIS VDDLDSGLNG KVICSIGKDV PFALTPSVQE KMFSLFAWCQ
     CAGKIPTLAC LLCI
//