ID A0A3Q0S1C8_AMPCI Unreviewed; 619 AA.
AC A0A3Q0S1C8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=T-box transcription factor 21 {ECO:0000313|Ensembl:ENSACIP00000016597.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000016597.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000016597.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR STRING; 61819.ENSACIP00000016597; -.
DR Ensembl; ENSACIT00000017042.1; ENSACIP00000016597.1; ENSACIG00000012923.1.
DR GeneTree; ENSGT00940000166447; -.
DR OMA; SYYPEHP; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20203; T-box_TBX21; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF125; T-BOX TRANSCRIPTION FACTOR TBX21; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 158..343
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 343..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 67967 MW; 0F092AA1A8FCBD07 CRC64;
MGGIGGNLYL SMLNGTEAQT FGKNADISSH FHRGGKDLTE FKMGIQDARF YYADSVQSGQ
DALSYHPDQA MGVYGAQPAR LYAQTLSSCP YGGVRSPPRS GAGQGYIPTA GDGFPTGGKD
VYSPSPENYP ASFQHGYQRS PLYPLPGLQV CGKTQALLNN YPLWAKFHKF QTEMIITKQG
RRMFPFLSFN ISVLDPTAHY NVYVDVILAD QHHWRYQGGK WVQCGKAEGN MPGNRMYMHP
DSPNTGAHWM RQEVSFSKLK LTNNKGSTNN VAQMIVLQSL HKYQPRLHIV QVKEDGTEDA
FLSSKAQTFV FPETQFIAVT AYQNADITQL KIDHNPFAKG FRDNYDTLYA PPDSDRLTPS
PTEGQQLLPG SCXPQGYLSE QYMSPLPQSR FYGREHIGVG QQHKDPSASP GPHSRWYLSP
QQGVAPNRLD FTSSYEGDFS GNGFYKPLPL QTSAHHALSY YPDHPFASTS VSVSGATSAG
WSASRPTPQY LSHASKPGPS LGWFRPISSS SSSSSSSISP GNPRLHPPTL LDSLQPPLLQ
DKPKDTVGVV AEDPWLEPPS VKSADSGDSG LFEGGVGENK KRRVSPYTSS TENSPPPRSG
EVCEKDSNSD ADYYGYYTH
//
