ID A0A3Q0S1X7_AMPCI Unreviewed; 345 AA.
AC A0A3Q0S1X7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Aggrecan a {ECO:0000313|Ensembl:ENSACIP00000016822.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000016822.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000016822.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00323}.
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DR AlphaFoldDB; A0A3Q0S1X7; -.
DR Ensembl; ENSACIT00000017277.1; ENSACIP00000016822.1; ENSACIG00000013081.1.
DR GeneTree; ENSGT00940000155971; -.
DR OMA; PEFDAYC; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd03517; Link_domain_CSPGs_modules_1_3; 1.
DR CDD; cd03520; Link_domain_CSPGs_modules_2_4; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 2.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR000538; Link_dom.
DR PANTHER; PTHR22804:SF42; AGGRECAN CORE PROTEIN; 1.
DR PANTHER; PTHR22804; AGGRECAN/VERSICAN PROTEOGLYCAN; 1.
DR Pfam; PF07686; V-set; 1.
DR Pfam; PF00193; Xlink; 2.
DR PRINTS; PR01265; LINKMODULE.
DR SMART; SM00445; LINK; 2.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS01241; LINK_1; 2.
DR PROSITE; PS50963; LINK_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00323};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..345
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018644181"
FT DOMAIN 134..229
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 234..331
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DISULFID 180..201
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
FT DISULFID 278..299
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
SQ SEQUENCE 345 AA; 38725 MW; F7D4C290421C031F CRC64;
CVLLSFFVLC VFLSFTDPDD VLRNKLIVKM FPLMQDHTVE DPGAPTIAPL SHRIKWSFVT
KENVTTILVA LEGGVRITEN YKDRVQLLSY PGSPTDASIR ISELRSSDTG VYRCEVQRDI
EDSYDIVHVQ VQGIVFHYRA IMGRYSLTFE KANAACTQNS AVMASPEQLQ AAYDDGFHQC
DAGWLADRTV RYPIHSPRLN CYGDKEELPG VRTYGVRDLN ETYDVYCFAE KMTGRVFYTA
TAEKFTFSEA VVACSNKGAQ LATTGQLYLA WQGGMDVCNA GWLGDRSVRY PINIRRPQCG
GGLLGVRTVY LHTNQTGYPF PESRYDAFCY TGRSECALPH QQPTC
//
