ID A0A3Q0S260_AMPCI Unreviewed; 1133 AA.
AC A0A3Q0S260;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Bromodomain and PHD finger containing, 3b {ECO:0000313|Ensembl:ENSACIP00000018949.1};
GN Name=BRPF3 {ECO:0000313|Ensembl:ENSACIP00000018949.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000018949.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000018949.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q0S260; -.
DR STRING; 61819.ENSACIP00000018949; -.
DR Ensembl; ENSACIT00000019460.1; ENSACIP00000018949.1; ENSACIG00000014721.1.
DR GeneTree; ENSGT00940000155056; -.
DR OMA; XRSLLMP; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05512; Bromo_brd1_like; 1.
DR CDD; cd15572; PHD_BRPF; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF19; BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 197..247
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 251..372
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 574..644
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1004..1087
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 747..768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..808
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1133 AA; 126709 MW; 6706C9F1FA63DA8A CRC64;
MRKPRRKGQV AGGGGGDRSP SPYSLKASPS RETLTYAQAQ KVVEVELDGR LHRISILEPL
EVITEDEMMA QDISECNSNK ENSEQSSPPA SNPKSSTNKS PPSSKNMLET FTPVEAPPLP
AAYYRYIETS AEEEAEAEYD MDEEDTAWLE MVNADRTSEG YSAVSPETFE RLLDRLEEEA
YLEARSRAPP QSTIDDDAFC CVCLDDECLN SNVILFCDSC NLAVHQECYG VPYIPEGQWL
CRCCLQSPQK PVDCVLCPNR GGAFKQTSDG RWSHVVCAIW IPEVCFANTV FLEPVEGVSN
IPPARWKLTC YLCKQKGSGA SIQCHKANCY TAFHVTCAQR AGLFMKIEPV RETNINGTTF
SVKKTAFCEA HSPPGQETGS DDESEGRVVG SRGRASRGRS AYTEGPTTPK KGRKSDNDAK
TDKKKGKRNT ESTSRRTASP QVTVPQIPTS RLNIICKGIT LQKKNQFMQR LYKYWLLKRQ
SRNGVPLVRR LHSNIQTQRN TEQPEVDEKI SAAREALRYW QKLRHDLEKA RLLVELIRKR
EKLKREQVKV HQAALEMQLT PMLVLLRSTL DQLQEKDTAQ IFAQPVDIKE VPDYLEFISN
PIDFSTMRSK LESHSYRSVA DLEADFNLMV SNCLLYNSKD TVFHRAALRL RDLGGAILRH
AQRQATNTGL DLDTGMHLPE SPQKRDFYSC TWEDVDSVLD PENRLHMSME EQLKELLEKL
DFVTSMRCSG ARTRRIRLLR REINNIRAGY PPRTNPNHPT VSSLVSRGPQ SLECHLSPLL
SEDLKSTSPP TLEPTGPAPP PRQGDAPLEP PTLRPITGEP QSHSYPCKPS SPPTLHSEGQ
AVTNGLPELG VPPRPMTGGV GRRTSVLFKK AKNGAKLFKA RDNPLLNGKG PQDENTSNNS
SICALLGVAF SDFSSCFCSL ICCCSDFCFL FSGLTNGFNL HKDGGSDLEF SSCPVLHKEI
NLPPKRSLGK PALSKVPFLD IVNGDSDYTG NSSQTSEDEM ELEPLDLVWA KCRGYPSYPA
LIIDPEMPEE GLLHNGVPIP VPPKDVLRLG EQRQEETNEK LYLVLFFDNK RTWQWLPRDK
VTPLGVDDTA DKLRIMEGRK SSIRKSVQVA YDRAMIHQSR VSHSHGFVAS SYL
//
