ID   A0A3Q0S7P8_AMPCI        Unreviewed;       320 AA.
AC   A0A3Q0S7P8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=heme oxygenase (biliverdin-producing) {ECO:0000256|ARBA:ARBA00012360};
DE            EC=1.14.14.18 {ECO:0000256|ARBA:ARBA00012360};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000020804.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000020804.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the heme oxygenase family.
CC       {ECO:0000256|ARBA:ARBA00006134}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   STRING; 61819.ENSACIP00000020804; -.
DR   Ensembl; ENSACIT00000021346.1; ENSACIP00000020804.1; ENSACIG00000016136.1.
DR   GeneTree; ENSGT00390000017673; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004392; F:heme oxygenase (decyclizing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006788; P:heme oxidation; IEA:InterPro.
DR   CDD; cd19165; HemeO; 1.
DR   Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR   InterPro; IPR002051; Haem_Oase.
DR   InterPro; IPR016053; Haem_Oase-like.
DR   InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR   InterPro; IPR018207; Haem_oxygenase_CS.
DR   PANTHER; PTHR10720; HEME OXYGENASE; 1.
DR   PANTHER; PTHR10720:SF3; HEME OXYGENASE; 1.
DR   Pfam; PF01126; Heme_oxygenase; 1.
DR   PRINTS; PR00088; HAEMOXYGNASE.
DR   SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR   PROSITE; PS00593; HEME_OXYGENASE; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        302..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   320 AA;  36627 MW;  2367E5D98E52AB92 CRC64;
     MEHYQIWIGL PRAQTSTLLK QCGIILTENR TNKNLSELLA EGTKESHDRA ENCQFVKDFL
     RGRIKRELFK VSTAALYFVY SAMEEEIEKN KDHXHIAPIY FPAELHRREA LAQDLEYFYG
     EDWENQISLS TGTKPYVDRI HEVGEKDPVL LVAHSYTRYM GDLSGGQILK KVAQRALKFP
     STGEGLNFYQ FEGIHSHKGF KQLYRSRMNE LELDAETKDR IVEESNQAFG FNMMVFTELE
     ELGKTIKEEV QDAGFGHSHA EIMQGGDISK CPYYAAKMAI SGNPTYACQL AMMLLRHPPC
     QVALAAWMAI LAGFTAWYFM
//