ID   A0A3Q0S854_AMPCI        Unreviewed;       414 AA.
AC   A0A3Q0S854;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Divergent protein kinase domain 1Ab {ECO:0000313|Ensembl:ENSACIP00000020939.1};
GN   Name=DIPK1A {ECO:0000313|Ensembl:ENSACIP00000020939.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000020939.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000020939.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004648}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004606}.
CC   -!- SIMILARITY: Belongs to the DIPK family.
CC       {ECO:0000256|ARBA:ARBA00006338}.
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DR   AlphaFoldDB; A0A3Q0S854; -.
DR   Ensembl; ENSACIT00000021485.1; ENSACIP00000020939.1; ENSACIG00000016272.1.
DR   GeneTree; ENSGT00390000006452; -.
DR   OMA; YMRIKYL; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022049; FAM69_kinase_dom.
DR   InterPro; IPR029244; FAM69_N.
DR   PANTHER; PTHR21093:SF4; DIVERGENT PROTEIN KINASE DOMAIN 1A; 1.
DR   PANTHER; PTHR21093; UNCHARACTERIZED; 1.
DR   Pfam; PF12260; PIP49_C; 1.
DR   Pfam; PF14875; PIP49_N; 1.
DR   SMART; SM01299; PIP49_N; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..163
FT                   /note="FAM69 N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01299"
SQ   SEQUENCE   414 AA;  46994 MW;  7CA8C7DFADD88384 CRC64;
     MCCQQARFSY LHMKYLFFSW LAVFVGSWIV YVEYSSYTEL CRGHECKNSI CDKYKKGVID
     GSACSSLCEK QTLYLRKCYT ANPNSQVYSG SWGDLEGVIK CQMEEAPHYD LGGEPRKEAA
     AAFNKPTKGT SVEKFREMII EHLKAKVGDQ ANLADLATQV LSIADGNKDS HISLPEARST
     WALLQLNEFL LALVLHDREH TPKLLGFCGD LYVMEKVPHA PLYGISLPWI IEMWIPAGLR
     RSMDQWFTPS WPHKAKISIG LLELVEDIFH GTFGSFLMCD VSATTFGYND RHDLKVMDAR
     YIVPEAIFQE VIRQQRCDVD EDCLYGADCL TSCDLTKHRC TTEVTRPNLA KACDALKDYI
     LRGAPSDVRE ELEKQLYACI ALKGLAEQME IEHSLILNNL KTLLWKKISH TKDS
//