ID   A0A3Q0SAC6_AMPCI        Unreviewed;       548 AA.
AC   A0A3Q0SAC6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Dystrobrevin, beta b {ECO:0000313|Ensembl:ENSACIP00000021784.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000021784.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000021784.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the dystrophin family. Dystrobrevin subfamily.
CC       {ECO:0000256|ARBA:ARBA00009563}.
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DR   AlphaFoldDB; A0A3Q0SAC6; -.
DR   STRING; 61819.ENSACIP00000021784; -.
DR   Ensembl; ENSACIT00000022356.1; ENSACIP00000021784.1; ENSACIG00000016910.1.
DR   GeneTree; ENSGT00940000153897; -.
DR   OMA; MMREMEM; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16244; EFh_DTN; 1.
DR   CDD; cd02334; ZZ_dystrophin; 1.
DR   Gene3D; 3.30.60.90; -; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   InterPro; IPR017432; Distrobrevin.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR015153; EF-hand_dom_typ1.
DR   InterPro; IPR015154; EF-hand_dom_typ2.
DR   InterPro; IPR000433; Znf_ZZ.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR12268:SF22; DYSTROBREVIN BETA; 1.
DR   PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR   Pfam; PF09068; EF-hand_2; 1.
DR   Pfam; PF09069; EF-hand_3; 1.
DR   Pfam; PF00569; ZZ; 1.
DR   PIRSF; PIRSF038204; Distrobrevin; 2.
DR   SMART; SM00291; ZnF_ZZ; 1.
DR   SUPFAM; SSF47473; EF-hand; 2.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS01357; ZF_ZZ_1; 1.
DR   PROSITE; PS50135; ZF_ZZ_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00228}.
FT   DOMAIN          238..294
FT                   /note="ZZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50135"
FT   REGION          464..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          375..455
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   548 AA;  62081 MW;  5A0D3CA9661FD2C0 CRC64;
     MIEEGSKRGK AMVEKRQLFM EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDVWNMIE
     AFRDNGLNTL DHNAEINVSR LETILSSIYY QLNKRLPTTH QINVEQSIGL LLNFMVATYD
     SESHGKLTVF SMKAMLATMC GGKIVDKLRY IFSQISDSSG VMVFAKFDQF LREVLKLPTA
     VFEGPSFGYT EHSVRTCFPQ QKKIMLNTFL DVLMADPPPQ CLVWLPLMHR LANVENVFHP
     VECSYCRSES MMGFRYRCQQ CHGYQLCQSC FWRGHANGPH SNQHQMKEHS SWKSPAKKLS
     HAISKSLGCV PIGEPPHPVF PEQAERPQEL THTVVLESPS RLDEEHRLIA RYAARLAAEA
     GNSTQQCPPT DLSFNFDANK QQRQLIAELE NKNREILQEI QRLRLEHEQA SQPTPEKAQQ
     NPTLLTELRL LRHRKDELER RMSALQESRR ELMVQLEGLM RLLKSQSGGS PHSSPSHGAG
     CSMPMPIRST SAGSTPTHTP QDCLAGVGGD VLEAFAQGVP RNLRNDLLVA ADSITNTMSS
     LVKELHSG
//