ID   A0A3Q0SQQ7_AMPCI        Unreviewed;       489 AA.
AC   A0A3Q0SQQ7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Leucine-rich repeats and guanylate kinase domain containing {ECO:0000313|Ensembl:ENSACIP00000025666.1};
GN   Name=LRGUK {ECO:0000313|Ensembl:ENSACIP00000025666.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000025666.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000025666.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q0SQQ7; -.
DR   Ensembl; ENSACIT00000026337.1; ENSACIP00000025666.1; ENSACIG00000019860.1.
DR   GeneTree; ENSGT00940000157992; -.
DR   OMA; REHMSHM; -.
DR   Proteomes; UP000261340; Unplaced.
DR   CDD; cd00071; GMPK; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23117; GUANYLATE KINASE-RELATED; 1.
DR   PANTHER; PTHR23117:SF18; LEUCINE-RICH REPEAT AND GUANYLATE KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   Pfam; PF14580; LRR_9; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SMART; SM00365; LRR_SD22; 3.
DR   SUPFAM; SSF52075; Outer arm dynein light chain 1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   4: Predicted;
FT   DOMAIN          217..404
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50052"
FT   REGION          446..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  55234 MW;  DAFB5A626A5F1C35 CRC64;
     EVNFSHNRMT KMKDLSDCVL LTKLDLDNSF CEISGLEQCC RLTHLSLAHN KISRISGLGS
     LPLTHLCLRG NQLERIEGLE HLKSLQVLDL SQNRITSLSG LQNLHLLGSI NLEKNLQISE
     IQECKHVHDL LLLRDLNLLG NPVQEQPDYK LAVIFLLQHL TVLDQEKVSA EEKVSSVNKY
     DPPMDVVAAR DHMTHLVYQL MQPQILYETL PSADSPYPML VMTGPQGCGK RELAHRLCQE
     FNKYFAYICH TTRGPYFGEE NGLDYHFVSQ EVFQNMIHMG KFIQTIQYGG HSYGLTRDAI
     EDVAREGLAC CVHMELEGVF SLKKSYFEPR YILLIPTQVE KYIGHLKSRG LYTPAQIDIA
     VSRIQLYANT SSQRPGFFDN VIPDWEEAYQ TLSQAVKEYL LLEELEEGEN NRASPDNTST
     ELASIRRREQ LVREALVGKS PGVYSQLFKQ TPNDPHPGAD QLAAAVSPSS DRRPGSNVKP
     ILPPIPTGR
//