ID A0A3Q0SR03_AMPCI Unreviewed; 106 AA.
AC A0A3Q0SR03;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Potassium voltage-gated channel subfamily E member 2 {ECO:0000256|ARBA:ARBA00039513};
DE AltName: Full=MinK-related peptide 1 {ECO:0000256|ARBA:ARBA00041657};
DE AltName: Full=Minimum potassium ion channel-related peptide 1 {ECO:0000256|ARBA:ARBA00042904};
DE AltName: Full=Potassium channel subunit beta MiRP1 {ECO:0000256|ARBA:ARBA00042937};
GN Name=KCNE2 {ECO:0000313|Ensembl:ENSACIP00000022645.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000022645.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000022645.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Apical cell membrane
CC {ECO:0000256|ARBA:ARBA00037861}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00037861}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004251}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the potassium channel KCNE family.
CC {ECO:0000256|ARBA:ARBA00005688}.
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DR AlphaFoldDB; A0A3Q0SR03; -.
DR STRING; 61819.ENSACIP00000022645; -.
DR Ensembl; ENSACIT00000023248.1; ENSACIP00000022645.1; ENSACIG00000017630.1.
DR GeneTree; ENSGT00940000154497; -.
DR OMA; RIFVTYM; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR InterPro; IPR000369; K_chnl_KCNE.
DR PANTHER; PTHR15282; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3; 1.
DR PANTHER; PTHR15282:SF8; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 2; 1.
DR Pfam; PF02060; ISK_Channel; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 106 AA; 12332 MW; 8F0C22090F3FA4E9 CRC64;
MTASDWSNFT LRLEESLTNT LSHFLDNWRR NVTAAANALE NTMAEENFRD VTWYLAVMIG
IFAFILVAML VSTVKSKRRE HSNDPYHQYI KEDWTAQIQQ SDTASR
//
