ID A0A3Q0SUZ6_AMPCI Unreviewed; 542 AA.
AC A0A3Q0SUZ6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2) {ECO:0000313|Ensembl:ENSACIP00000025493.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000025493.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000025493.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR AlphaFoldDB; A0A3Q0SUZ6; -.
DR STRING; 61819.ENSACIP00000025493; -.
DR Ensembl; ENSACIT00000026162.1; ENSACIP00000025493.1; ENSACIG00000019734.1.
DR GeneTree; ENSGT00940000155348; -.
DR OMA; DCVDHEQ; -.
DR Proteomes; UP000261340; Unplaced.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF68; MEMBRANE PROTEIN, PALMITOYLATED 2A (MAGUK P55 SUBFAMILY MEMBER 2); 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 46..104
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 132..211
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 217..285
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 340..527
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
SQ SEQUENCE 542 AA; 60886 MW; 1AB46AB8B4B93BBD CRC64;
MQVPQVLDAM SDSTASSTTA NDLDLIYLKG IMESPLQEES LKEPRLSPVR ENNMELLQEI
LRDLDPFTHR SDTAAELASI LTQPHFQSLL ETHDSVAAQA CESPPPSPCD FVDHEPEDSQ
AHNHLPSDAI RMVGIRKIAG EHLGVTFKVE GGELVIARIL HGGMIDQQGL LHVGDIIKEV
NGREVGRDPR VLQEELQAAS GIVVLKILPS YHETIAPRQV FFKCHYDYDP ANDNLIPCKE
AGLRFETGDI LQIVNQDDVN WWQARHVEGG SAGLIPSQML EEKRKAFVKI DVELAPAGNL
CTGIGKKKKK MMYVTTKNAE FDRHEILLYE EVAKVPPFKR KTLILIGAQG VGRRRLKNKL
LLRDPQLFGT IIPYTSRKPK KGERESRMFA FTSRSKMETD IKNGRFLEHG EYDGNLYGLK
IDSIHEVVEA GRVCILDANP QSLKVLRTSE FLPYIVFLQA PEFEVLKAIN QSAVEAEVVT
KTLTDEELQR TCNESAKIQA AYGHYFDLSI VNDNLDETYR TVKAALETVS KNPQWVPVTW
VF
//
