ID   A0A3Q0SWK3_AMPCI        Unreviewed;      1004 AA.
AC   A0A3Q0SWK3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b {ECO:0008006|Google:ProtNLM};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000024400.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000024400.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   STRING; 61819.ENSACIP00000024400; -.
DR   Ensembl; ENSACIT00000025043.1; ENSACIP00000024400.1; ENSACIG00000018941.1.
DR   GeneTree; ENSGT00940000154756; -.
DR   OMA; IRKGLMN; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 1.
DR   CDD; cd00096; Ig; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR35971:SF4; OBSCURIN; 1.
DR   PANTHER; PTHR35971; SI:DKEY-31G6.6; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF07679; I-set; 8.
DR   SMART; SM00060; FN3; 1.
DR   SMART; SM00409; IG; 8.
DR   SMART; SM00408; IGc2; 6.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 8.
DR   PROSITE; PS50853; FN3; 1.
DR   PROSITE; PS50835; IG_LIKE; 7.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          10..100
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          110..198
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          272..360
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          363..446
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          542..643
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          727..815
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          819..904
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          911..987
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   COILED          209..236
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1004 AA;  111509 MW;  8E79C68CAC13043A CRC64;
     MDQNLFGGAP RFLTRPKAFS VCVGKDATLS CTIVGSPTPL ITWEKDKLKL TSGGRFKTVE
     DGDVYRLTIY DLTLEDSGQY MCRAKNSVGE AYAAVTLKVA LPTEMSQKAP VFMVKPNSAR
     VGLGGDVVFH CRVAAHPEAN FEWEKDGRYL GETNRIKIVS DSNSSTLKIQ SVRNLDSGTY
     TCRAQNTVGR AQAAAALVVD XQDSHHQVAD KSNSLLSHLQ KRKEEMKKDI SIYRTEESST
     SVSSSSTAKI TDAFSSLSLE HELRASALAK LPKGVFTRTC TVTEGKHAKL SCFVTGHPKP
     HIIWRKDGTN ISEGRRHVIY EDQAENFILK ILYCKQNDNG LYTCNATNMA GQTYSAVLVT
     VKPKVPFRRK LQDVEVQEKT SATLMCEVPL ISTHTNWFME ETRLQQNTKY RMEEEGTLRR
     LTIHNVTTND DGVYICEMKE GSRTVAELTV LNITKKLPRR TVVPVSDTVI FCVELEHPCP
     DAYWTRNGEK LKEDSRISIA CMLRQYTLTI RDCQAEDSGE VAFVAGDCKT STRFSVTARK
     HPPDPPVDAV VQNKTESSIT IQWSPPDSDR PVPIKGYIVE RRKVGAQMWQ RCNAEETIVS
     TEITICSFTE EASYQFRISA INDFGQSAYL EVPGNVYLPT AEIRKGLINS TAVSGEEFAI
     SVELSAVCSG FWSLNGRLLR SGADYLITRS KNIHTLLIRV VTMEMNGAEV KFVGGGSQSS
     CILSVKPSVR FTNKSDHLEV VTCSAQATAQ LTAEVSDYET QVVWMNNGRE LKMGKKYEYV
     INDRKRILMV HNVTEEDVGI YECVLPDDKM SMQLTLREPA KFLNKARGTM GLSSTLKGDL
     ELTCEVSSAS AAVVWRKDQV EITEDQRTTI ISKGTQRKLI IKNAKKSDEG HYSCATAADK
     VTFQVKIKSQ SAFINTESVQ KEVKATLSQK ATLSCDVADT KTEVKWYKDG KLLTSSKTIH
     TESKGKNRQL VIDCVEKKDA GEFICEAGTE KLAFKLQVAG KGGF
//