ID A0A3Q0SX68_AMPCI Unreviewed; 944 AA.
AC A0A3Q0SX68;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MAM domain containing glycosylphosphatidylinositol anchor 1 {ECO:0000313|Ensembl:ENSACIP00000028221.1};
GN Name=MDGA1 {ECO:0000313|Ensembl:ENSACIP00000028221.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000028221.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000028221.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q0SX68; -.
DR STRING; 61819.ENSACIP00000028221; -.
DR Ensembl; ENSACIT00000028965.1; ENSACIP00000028221.1; ENSACIG00000021856.1.
DR GeneTree; ENSGT00940000159201; -.
DR OMA; NSWQQAH; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 2.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR45080; CONTACTIN 5; 1.
DR PANTHER; PTHR45080:SF33; MUSCLE ASSOCIATED RECEPTOR TYROSINE KINASE; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 5.
DR Pfam; PF00629; MAM; 1.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00137; MAM; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 6.
DR PROSITE; PS50060; MAM_2; 1.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 25..126
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 133..231
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 240..324
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 339..433
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 441..534
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 540..627
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 639..739
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 747..921
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 771..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 105790 MW; E1AD42B6CD6861F3 CRC64;
NSTAPLDLLS VLHKACNYTE QLPSPANAQI VHSGAACNVK DDNMSERIYT IKEGDTLVLQ
CIVKGHPRPQ VRWTKTAGSA SDKFQETSIY NETLRIEGIQ RVQGGRYYCK ADNGVGVAAI
KSIRVDVQYL DIPVLTVHQT ISDVRGSYYQ EKTVFLRCTV NSNPPARFIW KRGDMLIEQS
KDNGVDIYEP LYTQGETKVL KLKNLRPKDF ADYTCQVSVR NVCNIKDKSV TFRLTNATTP
PMIRLSVNDT VVVDPGQDVH ITCEVTAGFP LPTVIWSRYP GPLPLSAQVR GATLILRAVT
PADAGFYNCT AVNNVGNPAR KNVNLIVRTM SNLTFQITPD SNKDSETIQM GRDLKLSCHV
DATPQDKVNY TWYKNGVPVF NSDSLILLRS DPDMAPGTSS LEIVDMKFRD LATYSCVASF
PGSTVRELRV DVNISQNSVS PPVLSVPSGG QVVSVREGGN AELVCLVVDG KPRPPILWSR
TEKDLLMPSG KPIVETPDGR LRIKNISRDM MGAYRCQTAP YNGLNIKRRE AQVQLNVQYP
PILDPVFQDV RSRNYQMVTL RCTVQRSNPP RLTDIRWFRN GDFIRMPMPD LKETPELKFK
LEPTNNGSYE CRVSNSVGTS TCTFNVSAQP YNAEFYFDTP NPVRILKGNN YSYNLQWTQK
DPEATDRIIG YWVNVRKNKQ NLLSKQIDLK GKAPEKGVLM SYTISDLKIP LSYEVRLAPI
TTYSTGDYVS RIIQYSEPYT YPRPSDHVCG FEDERICGFS QDRSDVFDWT RQNHLTQNPK
RSANTGPDTD RSGTKEGYYM YIEASRPRTQ GDKALLLSPL FNITSSRGPK GRVPYCVSFY
YHMKGKHIGT LNVYLKVRSI ASVDRVMWTK SGHQGPDWKK AFFDITPSGP FQIVFEGIRG
SGFEGDIAID DVSITRGECK QQNTVANAGK TGKIYCHFGV CVCV
//
