ID   A0A3Q0SYX3_AMPCI        Unreviewed;       831 AA.
AC   A0A3Q0SYX3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000028947.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000028947.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   Ensembl; ENSACIT00000029714.1; ENSACIP00000028947.1; ENSACIG00000022324.1.
DR   GeneTree; ENSGT00940000163991; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR01535; VOMERONASL2R.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        564..588
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        603..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        636..659
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        680..702
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        714..747
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        759..779
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        791..815
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          565..829
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   831 AA;  91716 MW;  E35460F4F6B38BBE CRC64;
     MFTGAWTGTV ASSVNCKLQV SARLPAFSMD GDFIIGGVFS LHSYMHTVNN NYTTMPEPVR
     CRGSIGPREL RFSRAMVFAI GEINNSTELL PGISLGYQIY DSCGSVPVAV DVAFQFLNSL
     DPMFYIGSNC SQFGMMMAVV GESGSTPSIS MSRVISPFNI PQVSHFATCA CLSDKQQYPS
     FFRTIPSDQF QADALAKLVK HFGWTWIGAV RSDSDYGNNG MASFLKAAQK EGICVEYSIS
     FYRTDPQSKI QKVADVIRRS TAVVVVAFAA LGDMKILLEE LSXEPFPPHQ WIGSESWVTN
     PELTRFSFCA GAIGFGIQKS VIPGLKDFLL NLTRFWEDAF NCRLNKSAAA DKKVCDGSED
     IHNLQSQYTD TSQLRITNMV YKAVYAIAHA IHNAVCQGQS ASFKCDKLTK LEPTQVLTQL
     KKVHFSQNGY DVSFDANGDP VAIYELVNWQ KSETGKTELV TVGLYDASLP VGQEFRINRN
     ITWMEGNMQV PGSVCTASCP PGTHKVLQKG KPICCYDCIP CPDGEISNTT DSPDCSSCHK
     EFWPNAKRDT CIPKPVEFLS FQDLLGIILS TFSVLGASLT IIALIVFFRH RTSPIVRANN
     SELSFLLLIS LTLCFLCSLT FIGAPSEWSC RLRHTAFGIT FVLCISCVLG KTIVVLIAFK
     ATRPGSNVTK WFGPPQQRMT VLSFTLMQVL ICTIWLVCSP PFPVKNLSTY KDKIILECAL
     GSAIGFWAVL GYIGLLAAFC FVLAVLARKL PDNFNEAKLI TFSMLIFCAV WITFIPAYVS
     SPGKFTVVVE IFAILASSFG LMLCMFAPKC FILLFKPEKN TKKYLMKKNQ S
//