ID A0A3Q0SZE7_AMPCI Unreviewed; 577 AA.
AC A0A3Q0SZE7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Nectin cell adhesion molecule 4a {ECO:0000313|Ensembl:ENSACIP00000027033.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000027033.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000027033.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR AlphaFoldDB; A0A3Q0SZE7; -.
DR STRING; 61819.ENSACIP00000027033; -.
DR Ensembl; ENSACIT00000027741.1; ENSACIP00000027033.1; ENSACIG00000020942.1.
DR GeneTree; ENSGT00940000157535; -.
DR OMA; KNHQHPP; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23277:SF11; NECTIN-4; 1.
DR PANTHER; PTHR23277; NECTIN-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 319..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..130
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 215..316
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 384..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..435
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 63886 MW; 79E103E8A5471D2D CRC64;
MDSWVYSSLL VRVIPGDFVE PPPNHSLISM AEDRTILPCH YKPSNGTVVV QVTWLQEKPD
GTKEQIITAH HINGQTAFGS WSQRVHFKSN QPTVDSSLVI MGTEVSDEGK YICRVSAFPS
GNFDTHMSLI VWTHPISSVE PVTVVEGQDY RQVASCRSVA RPPPRLTWDT DLNGQSVNRS
SESGAISSHF SLHPLRNMNG KKLDCLVWHP TYSEPRRLKN QLVVLFPPHA EVSGYSGNWH
VGLENAALSC VSGGNPKPHV FTWIRKDGEL PKGVIQHANG TLAFERPLNL SDAGTYQCVA
TNEVGVGKAE EQKNLENTMM FIVGGVAIAL LILLLTIVVA VTCHHKRKNK RLKRELTEKK
YEIIRHENIP LRVEGTLRSS LSSLGQAQCR DSRSTLSGGR GGVGAYDSLG RPALYNNSRR
GRERPVDREE ESRLRVERYV KNNSLSLPET HFHPPLTPSS FQRMQSHNFM RPVNGSAIVP
SDVGSRQGSV TKNHQHPPMS STCPPIRDDD DEVDEGLGGP ASQERPFDQD SETNSSQVSE
ATSMHCQHSN GMLKHKRLPS PTLVSPHASI IHKAQIV
//
