ID   A0A3Q0T0W6_AMPCI        Unreviewed;       527 AA.
AC   A0A3Q0T0W6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=GDNF family receptor alpha 3 {ECO:0000313|Ensembl:ENSACIP00000027593.1};
OS   Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC   Cichlasomatinae; Heroini; Amphilophus.
OX   NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000027593.1, ECO:0000313|Proteomes:UP000261340};
RN   [1] {ECO:0000313|Ensembl:ENSACIP00000027593.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDNFR family.
CC       {ECO:0000256|ARBA:ARBA00005961}.
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DR   AlphaFoldDB; A0A3Q0T0W6; -.
DR   STRING; 61819.ENSACIP00000027593; -.
DR   Ensembl; ENSACIT00000028322.1; ENSACIP00000027593.1; ENSACIG00000021373.1.
DR   GeneTree; ENSGT00940000165282; -.
DR   OMA; NSISWMG; -.
DR   Proteomes; UP000261340; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0014707; P:branchiomeric skeletal muscle development; IEA:Ensembl.
DR   Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR   InterPro; IPR016017; GDNF/GAS1.
DR   InterPro; IPR037193; GDNF_alpha.
DR   InterPro; IPR003438; GDNF_rcpt.
DR   PANTHER; PTHR10269:SF15; GDNF FAMILY RECEPTOR ALPHA-3; 1.
DR   PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR   Pfam; PF02351; GDNF; 2.
DR   PRINTS; PR01316; GDNFRECEPTOR.
DR   SMART; SM00907; GDNF; 3.
DR   SUPFAM; SSF110035; GDNF receptor-like; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          21..102
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          152..232
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          244..338
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
SQ   SEQUENCE   527 AA;  59551 MW;  CB54106E2387ADDB CRC64;
     MPCFDVLSSP NFNFAASTTD CVEAYRVCSA EPRCEALYRG LDLCATDTAM SPLADQVASE
     CLERQEALLA NYPPLQNCKC QRGFRKEELC LRIYWRLRLM PGQCGWIVLG CINRFQFPYP
     PQKSVLLDVF IILTLTLPPA SSFMQLDGEN QCLKAAQDCG LYEKCGNLRS EYVLACTKPI
     PGTNRCYQHK CHRSLRRFLE RVPEEYSLGV LFCPCTNTLC GERRRKTIVP SCSYQDMDGL
     PPNCLHQQSF CRREDLCRSR LADFLNNCQP SHLTASGCLK DSAGLCLRAY AGLIGTIMTP
     NYISNSSADV SLWCNCDGSG NQWQECLKLQ RLFTHNPCLR ESMQRCTPDQ VHVCMHTHTH
     THTHTHTHTH THTHTHVVIW LFLQAGNAIS WMGSPGSLPA DITQPPAPRP SPLVQKDELL
     SSNHLPEHNN IVSTLITAHH HCHILNYLSD FYPKAFSVIF GLSTSHHCHA VFCLFIMRLS
     PLLGFLSFIP HLLCWCLIFD GFKLWVCKNQ AHILSIVTKS FNLPQGM
//