ID A0A3Q0T150_AMPCI Unreviewed; 383 AA.
AC A0A3Q0T150;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=ETS transcription factor ELK3 {ECO:0000313|Ensembl:ENSACIP00000030871.1};
GN Name=ELK3 {ECO:0000313|Ensembl:ENSACIP00000030871.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000030871.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000030871.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR AlphaFoldDB; A0A3Q0T150; -.
DR STRING; 61819.ENSACIP00000030871; -.
DR Ensembl; ENSACIT00000031678.1; ENSACIP00000030871.1; ENSACIG00000023869.1.
DR GeneTree; ENSGT00940000157129; -.
DR OMA; HRPIKME; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF172; ETS DOMAIN-CONTAINING PROTEIN ELK-3; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 5..85
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 98..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 41905 MW; 2CA67C7605DE6CA0 CRC64;
MESSITLWQF LLQLLLDQSH KHLICWTSND GEFKLLKSEE VAKLWGLRKN KTNMNYDKLS
RALRYYYDKN IIKKVIGQKF VYKFVSFPEI LKMDPAVVES GRSSEESGGV ASEPEAEDED
GGERNQYLHS GLYSSFTISS LQHSLEQHRP IKTEPRSDRP DDGSSVIRFM TNRGHSSIPS
TPPPSSTENT HSSRLSPQMA RSSSSSSSPP QSPTHMLVRG GRQSTDTNEL EPNAQPLNLS
SGQRERERSQ STTTPERRGL ANGTPLKGRK PKGLEISAPS RLLTGSDLVS IALNSPALPS
GSLTPAFFTA QTPSGLLLTP SPLLSNIHFW SSLSPVGPLS PAQLQSHAPL FQFPTLLNGP
IPVPLPGVDT SSPLLLSSSS HKS
//
