ID A0A3Q0T5L5_AMPCI Unreviewed; 643 AA.
AC A0A3Q0T5L5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Neurocan b {ECO:0000313|Ensembl:ENSACIP00000031538.1};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000031538.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000031538.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00323}.
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DR AlphaFoldDB; A0A3Q0T5L5; -.
DR STRING; 61819.ENSACIP00000031538; -.
DR Ensembl; ENSACIT00000032366.1; ENSACIP00000031538.1; ENSACIG00000024364.1.
DR GeneTree; ENSGT00940000158649; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd05902; Ig_Neurocan; 1.
DR CDD; cd03517; Link_domain_CSPGs_modules_1_3; 1.
DR CDD; cd03520; Link_domain_CSPGs_modules_2_4; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 2.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR000538; Link_dom.
DR PANTHER; PTHR22804; AGGRECAN/VERSICAN PROTEOGLYCAN; 1.
DR PANTHER; PTHR22804:SF24; NEUROCAN CORE PROTEIN; 1.
DR Pfam; PF07686; V-set; 1.
DR Pfam; PF00193; Xlink; 2.
DR PRINTS; PR01265; LINKMODULE.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00445; LINK; 2.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS01241; LINK_1; 1.
DR PROSITE; PS50963; LINK_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00323};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 35..144
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 146..241
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 247..343
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT REGION 420..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..435
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 192..213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
FT DISULFID 290..311
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00323"
SQ SEQUENCE 643 AA; 71065 MW; 6E678C332EC0076F CRC64;
SFHLERGTIN IFWSEDLSVV NMRKVTHQTI SEELSKTVLL PCLFTLRPSP SSFHEPPRIK
WTKVWGQRGS DGLQKEQSVL VAKDNVVKVK KAFQGRVTLP GYNKNRYNAS LALTGLRSSD
SGLYRCEVVV GINDEQDTVP LEVTGVVFHY RAPHDRYALS FADAKRVCVE NSAAIATPAQ
LQATFADGYD NCDAGWLSDQ TVRYPIQSPR PGCYGDREDS PGVRNYGNRS PDELFDVYCF
AKRLQGEVFH STVPEKLSLA TASTHCHSLG AQLATVGQLF LAWQAGLDQC DPGWLADGSV
RYPINVPRKN CGGDEPGVRT VYNNPNRTGF PDTTALFDAY CYRGTKRVQA AEPQTLYQTA
HPEAEAMPLF TEAQDSARVP KTSSWTGLVD LDELGAPSIA GINNSSEISE EHVIIHLRPE
EDLDESQEEP KTTEPSQNES HNPKTTNSFG LSDLESLEKH GGSAHEKEDE SYFESDTPTL
SSIATFTPQV QTSNSILTDF VNTLIRPFRY WTQSEEGDET ERTSMVPEEK TTENQTQEEA
PSRNLSLPKP SGKKGSIDNA IMEHRSGPFS FMGPTSELQS PEEGLSNQEK EMMPLIQSVA
AIQNTGEGGT SPPPEERIMS PLADQSQSPV KGMSSAFNLY VYF
//
