ID A0A3Q0T5N2_AMPCI Unreviewed; 219 AA.
AC A0A3Q0T5N2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Ras-related protein Rab {ECO:0000256|RuleBase:RU367128};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000027465.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000027465.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: The small GTPases Rab are key regulators in vesicle
CC trafficking. {ECO:0000256|RuleBase:RU367128}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU367128}; Lipid-
CC anchor {ECO:0000256|RuleBase:RU367128}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270, ECO:0000256|RuleBase:RU367128}.
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DR AlphaFoldDB; A0A3Q0T5N2; -.
DR Ensembl; ENSACIT00000028188.1; ENSACIP00000027465.1; ENSACIG00000021228.1.
DR GeneTree; ENSGT00940000165121; -.
DR OMA; WDSDTVI; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005802; C:trans-Golgi network; IEA:UniProtKB-UniRule.
DR GO; GO:0031982; C:vesicle; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd04107; Rab32_Rab38; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR030697; Rab29/Rab38/Rab32.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47981; RAB FAMILY; 1.
DR PANTHER; PTHR47981:SF44; RAS-RELATED PROTEIN RAB; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU367128};
KW Lipoprotein {ECO:0000256|RuleBase:RU367128};
KW Membrane {ECO:0000256|RuleBase:RU367128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU367128};
KW Prenylation {ECO:0000256|RuleBase:RU367128}.
SQ SEQUENCE 219 AA; 24151 MW; AF4B99C090DA4F4E CRC64;
AAGRGSGPPP AAAMQQELLF KVLVIGDLGV GKTSIIKRYV HQIFSQHYRA TIGVDFALKV
LQWDNDTVIR LQLWDIAGQE RYGNMTRVYY REAVGALVVF DVTRASTFDA VLKWKADLDS
KVTLNHGRPV PAVLLANKSD QLASQPPKLD SFCRENGFVG WFETSAKENT NIEEAARCLV
EHILRNEESL VAEREPGSLV LSGCTATTKE HLSCSSCSK
//
