ID A0A3Q0T7E5_AMPCI Unreviewed; 755 AA.
AC A0A3Q0T7E5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Amphilophus citrinellus (Midas cichlid) (Cichlasoma citrinellum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; New World cichlids;
OC Cichlasomatinae; Heroini; Amphilophus.
OX NCBI_TaxID=61819 {ECO:0000313|Ensembl:ENSACIP00000029974.1, ECO:0000313|Proteomes:UP000261340};
RN [1] {ECO:0000313|Ensembl:ENSACIP00000029974.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR STRING; 61819.ENSACIP00000029974; -.
DR Ensembl; ENSACIT00000030760.1; ENSACIP00000029974.1; ENSACIG00000023194.1.
DR GeneTree; ENSGT00940000163991; -.
DR OMA; CHARVIL; -.
DR Proteomes; UP000261340; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR Gene3D; 3.40.50.2300; -; 4.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 474..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 668..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..724
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 474..738
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 755 AA; 83308 MW; E43F40174644CD03 CRC64;
MSALLGNSLC RDICHSGFQL WTNDINNSTE LLPGIRLGYQ IYDSCASVPV AVHVAFQFLN
SIDPVFYTDN DCSQSGMVVA VVGDSGSTPS ISISRLISAF NIPQVSHLAS CACLSDKQQY
LSFFRTIPSD QFQAEALAKL VKHFGWTWIG AVRSDSDYGN NGMASVYNVL YFLSRSKAVV
IVAFASFGDM KILLEELSRE XFPPRQWIGS ESWVTSTELA QFSFCAGAIG FGIPKSVIPG
FRDFLLNLSP SQVAASPVLT EFWEDAFNCS QKKVPASDKK VCDGTENIQN LQSQYTDTSQ
LRITNMVYKA VYAIAHAIHN XVCQGKNATA KCDKLTKLES KQLKKVNFSQ NGYDVSFDAN
GDPVAVYELV NWQKSESGIT EIRNITWMEG RIFIVFALCL SQVPVSVCSD SCPPGTHKVL
QKGKPICCYD CIQCPDGEIN SADCLPCHEE FWPNAKRDIC IPKPVEFLSF QDDLGIILAT
FSVLGACLAI MTAAVFFHHR TSPIVRANNS ELSFLLLISL TLCFLCSLTF IGAPSEWSCM
LRHTAFGITF VLCISCVLGK TIVVLMAFKA TIPGSNVMKW FGPPQQRMTV VSFTFIQVLI
CTVWLLLSPP FPMKNLTTYK EKIILECALG SPIGFWAVLG YIGVLAAFCF VLAVLARKLP
DNFNEAKLIT FSMLIFCAVW ITFIPAYVSS PGKFTVVVEI FAILASSFGL IMCIFAPKCF
IILFKPEKNT KKYLMNKNQS KYSSGSKMAN IAIVN
//
