ID A0A3Q1AI40_AMPOC Unreviewed; 451 AA.
AC A0A3Q1AI40;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Glial fibrillary acidic protein {ECO:0000256|ARBA:ARBA00018571};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000000688.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000000688.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A3Q1AI40; -.
DR STRING; 80972.ENSAOCP00000000688; -.
DR Ensembl; ENSAOCT00000014502.1; ENSAOCP00000000688.1; ENSAOCG00000003566.1.
DR GeneTree; ENSGT00940000159539; -.
DR OMA; IMAHQVH; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF9; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 89..397
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 107..230
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 284..375
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 451 AA; 51795 MW; BF748B984C5BAEF9 CRC64;
MESQRVQSSY RKRFGPQGSG STAVRVGGLS SSRFSWHGTP RNLTHSSPIS RISMGSASTA
LLLGSPADRL DFSADSLMKA QFKEIRTNEK MEMMGLNDRF ASYIEKVRLL EQQNKVLVAE
LNQLKGKEPS HLGDIYQEEM RELRRQVDGL TAGKARLEIE RDNLAADLAT LKQRLQDEIS
LRQDAENNLN GFRQDVDEAA LNRVQLERKI EALQDEINFL KKIHEEEQRE LQEQILAQQV
HVDLDVSKPD LTAALRDIRV QYESMASSNM QETEEWYRSK FADLTDAANR NAEALRQAKQ
EANEYRRQIQ VVTCDLEALR GTNESLERQL REMEDRCAME TAGYQDTVRS LEEEIQALKE
EMARHLQEYQ DLLNVKLALD IEIATYRKLL EGEESRITIP VQSFSNLQFR ETNLDTKTPE
AHVKRSILVR TVETRDGEII KESTTEHKDL P
//
