ID   A0A3Q1AJ05_AMPOC        Unreviewed;      1270 AA.
AC   A0A3Q1AJ05;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=DENN domain-containing protein 3-like {ECO:0000313|Ensembl:ENSAOCP00000001060.1};
GN   Name=DENND3 {ECO:0000313|Ensembl:ENSAOCP00000001060.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000001060.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000001060.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 80972.ENSAOCP00000001060; -.
DR   Ensembl; ENSAOCT00000013881.1; ENSAOCP00000001060.1; ENSAOCG00000003995.1.
DR   Ensembl; ENSAOCT00000013889.1; ENSAOCP00000001055.1; ENSAOCG00000003995.1.
DR   GeneTree; ENSGT00940000155784; -.
DR   OMA; QVWMGSQ; -.
DR   OrthoDB; 5354449at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR031815; DUF5074.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR12296:SF21; DENN DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF16819; DUF5074; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS50211; DENN; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          72..492
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REPEAT          1235..1270
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          57..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1270 AA;  143976 MW;  9B7EC92DB7BC9A8F CRC64;
     MADYLPAALL EACVVVGASS DKLQEVYQAF HSNGTPELPL LEPEVLHVLV PPFVSRPQAE
     SETLRPRGKR RRSFLRKKRE QLPSSAPTPG GGAADGKGGS EDISVPKDID LMALPQLCFP
     GGLQVTSEQK DEEFHFLVFT NVFGNKTHGV VMQCYRPIQE GTSFYQNGAD SSKLFSAYSF
     CVISKYPFFT ALKDCLSCLL IQLKTCRLSD MEDRVKEFAA KLTLVPVPPP GQLHLMFELR
     PLTIILPAKE DRDLPAVDLD LHLPFLCLRP QQLLQVICCL LQEQRVVLFS ADWSRLTLMA
     ECLLLFLQPL SWQQPYVPVL ARGMLDFLMA PTAFLMGCHL SHFAEVAAET EDLILINIDK
     GTVCTSSSDT IDLPDIPPAA AECFTQRCQS LKIHFDLDHW RHASSTDINE QRTQRRTWQQ
     NLNHNIQRVA LELIVNIFRD VSDHLNYEHR VFHSEEFLKT REPAEQLFYK KVLETHIFHS
     FLKDRLNKKM DNFTRMELGT RSEMQKMKAM VEVPRRPTMQ EIQARRKSSV TEIRLSKRLG
     MSLPNLGDDQ TISFQRNSLL TRIFVPDPGL KSPPKPVKVF KLPDFPASLS FHSVQSYYSE
     LIQQLGKAIF SVQNENSALL ARFYYLRGLI NTLCSRRLDA LSDFQNLYKT DTAIFPTHLV
     TFLVDSLHRD ERQQAQRRPE LKRLILKVKT DNEKQLVQPD DHVKKFQLPR QQLHQDEFVR
     CIQECRIVKD VTTIHRLFEA LADGQPQKVD PELFKIFYTF WKEAEAEAQD VSLPSEVIDH
     LDYSECVYKL SSCVKTSLGV GKIAMTQKRL FLLTEGRPGF LEITKFRDIQ EVKVATAPFL
     LVRIPSLRIQ TSGRPETFEA NLKTETELWN LVVKEMWAGR KMADQHKDPQ YMTQALTNVL
     LMDAVTGSLQ TQRSIAAASK LAYFDKIKHE VPMMVPKTTS ETLKHKINPS LDLAEPQTVH
     VLLYTPGQLT CNDSEAEMNP KLWVALSGGR VVVFDAASWS MLQACIQVGE SQVNCMMGLV
     QEQVWIGSQD SVIYIIDTHS MSCNKQLTEH RQEVTSLAMD TRDLHNSQLT YSCSCDGSIL
     QWDSSSLKVK RQFHLNCQRL SSIQVHDGTL WCCCDDSIVE LKKSGTAQRR ITLPSDLRST
     SSSFSSFVVI PERGQVWTGC ADSVDLCLWQ TNNHRHPPKR ISLPGTSGVT CMIRVKDQIW
     VGCCGRSSVG GECDGQLRSQ VLVVDPQSHA VEKELQGHSD SIQTLCSAED RYVLSGSARR
     DGKIAIWKVE
//