ID   A0A3Q1AKP7_AMPOC        Unreviewed;      1154 AA.
AC   A0A3Q1AKP7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000001309.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000001309.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005601}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q1AKP7; -.
DR   STRING; 80972.ENSAOCP00000001309; -.
DR   Ensembl; ENSAOCT00000013454.1; ENSAOCP00000001309.1; ENSAOCG00000004267.1.
DR   GeneTree; ENSGT00940000165903; -.
DR   OMA; YDRERAH; -.
DR   OrthoDB; 170190at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR   CDD; cd18078; DEXXQc_Mov10L1; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR049080; MOV-10-like_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF322; RNA HELICASE MOV10L1; 1.
DR   Pfam; PF13086; AAA_11; 2.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF21634; MOV-10_beta-barrel; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT   DOMAIN          538..604
FT                   /note="Helicase MOV-10-like beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF21634"
FT   DOMAIN          711..806
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          823..892
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          900..1110
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          339..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..711
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..380
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1154 AA;  128708 MW;  8C05160F454496B0 CRC64;
     MLTALRYMLS KLVSPLWRTV EVDGEDILCG TPGMEDISHL RGSVVTQLCL DYGMIDDTVY
     FTSGEVLGGV RLKEGDLVNC IAVRDGAQGG WKALRVEKSA DSWENGGRTS LEADSMQLRP
     LIGTVTSFDG NGGYINQTTY FPRHSLWKGY EPMKGDWVQV KYFINPTQWT TQAHSVTPLR
     YCRLDQVRIT SVYGNSGVVE DSVFFSLDSL LLPANYQPLP GHLVNMVVVE SNQSIFCWRA
     LCMAPFLQSC NASSSAALLQ ETELQSILEN KGGLDVTDYG QFGDVLIGER RELVLWIQNK
     GSETHRLKCC DFAGWDSEEQ FNLVTDSGLT PLSQKQALQE DCPESSEKQV RDAKELDKEN
     GEMQKETIHS TGVRREEREV DIPPGERLSI TVACQTKSLG SCAELLLLHF SSFTIGRRLE
     VTVGSEEENQ LHPSVPYSQS NAPPVSATPS HVITVSAPKD TPRLTKRRLP VFMPTYPVPQ
     ALRDCVEAQA DVLVVQPCLG EVLSPSNMHS RFSTLLWLEE LHAERELREF TITGALLRKG
     GVYLHLEVHG LSEGRPSLNI GDKILLRKLQ SDGLVMEYVS YVTEINDQDV SLRVNSEFQR
     RYLGEPLDVE FSYNRTTMRR CHNALDQTKL FEEILFPSRV TLQTPQWTGN WLDEEEKDQN
     KTVEDKKTPA IENGMVGSVS IDMKSKATQT KDGRLPSKPI PSRGQFFNPD LNPPQREAVK
     RILAGECRPI PYVLFGPPGT GKTITLIEAI LQVYHFLPSS RILVCTPSNS AADLICIRLH
     DSGYLHAASL ARVNASCRQN ESIPEVLRPY SREGEDIRHA AFHRIVVSTC SSAGMFHSLG
     IQVGHFTHVF LDEAGQATEP ESLIPISLVS ERDGQIVLAG DPRQLGPIVK SKLADAFGLG
     VSLLERLMAN SLYSRQDWGY NPKLTTKLIY NYRSHEALLT LPSKLFYQGE LRFKASKAIV
     DSLCQWKNLP KKSFPLLFHG VRGTEMREGS NPSWFNPVEA VQVMLYCCQL AKKLYNPVDA
     SDIGVIAPYK KQCEKIRVLL GKVGLSDVKV GSVEEFQGQE YLVIILSTVR SNESIQSDDL
     QSTLGFLSNP KRFNVAVTRP KALLLVVGNP HILIRDPCFR ALLQYCFING AYLGCDPPPS
     LRDSQIVAEE QRSA
//