ID A0A3Q1AKQ3_AMPOC Unreviewed; 623 AA.
AC A0A3Q1AKQ3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Epsin 1 {ECO:0000313|Ensembl:ENSAOCP00000001790.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000001790.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000001790.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR AlphaFoldDB; A0A3Q1AKQ3; -.
DR Ensembl; ENSAOCT00000012606.1; ENSAOCP00000001790.1; ENSAOCG00000004889.1.
DR GeneTree; ENSGT00940000160411; -.
DR OMA; NPWGQPQ; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF48; EPSIN-1; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 2.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 148..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..356
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 64191 MW; D5E6F8BCC3F0F257 CRC64;
MSTSSLRRQV KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMV
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVAQQCRENI YAVQTLKDFQ YIDRDGKDQG
VNVREKAKQL VTLLKDEERL REERIHALKT KEKMAQTSSA SSAPSAPSLG GSLSLGSHSG
GADPEQAWPQ SSGEEDLQLQ LALAMSKEEA EQEERLRRGD DLRLQMAIEE SKREKPKPEE
STLMELSAVD PWGAPPAAAA APGGSTGPSP PPTVPAPAAS GPWDSAPTDP WGVASPTSPT
STDPWGGGAP PTVAPPPDPW GETANRVNNV DPWGSSAVTP PSSDPWGPPV PPSTSSSGGP
VDPWASDGPV PEPISSDLWS ATAKHTNGTG DPERRGSSAA GCDSTGSPVP FNLSSLGSSL
PVRKTPESFL GPNAALVDLD SLVSSKPKPK QPPPPSISSS SAHNPFLQNT GSSPAPGMAV
TPGSTISSRG VSPTPASSNP FGVAPPMTSI SPQPSSLGLS GLRTSPVPPN PMLGLVQPGL
GPMGPMGVGA PGMGLGMMQA SPMGMPYSGL SPMAPPGPAL LGPGAPPPQL ILGGPSGPGG
VMGAGGSVGG GGAAGASTNP FLL
//
