ID A0A3Q1AN24_AMPOC Unreviewed; 1687 AA.
AC A0A3Q1AN24;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Kinesin-like protein KIF13B {ECO:0000313|Ensembl:ENSAOCP00000002129.1};
GN Name=KIF13B {ECO:0000313|Ensembl:ENSAOCP00000002129.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000002129.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000002129.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR Ensembl; ENSAOCT00000012049.1; ENSAOCP00000002129.1; ENSAOCG00000005286.1.
DR GeneTree; ENSGT00940000155500; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12473; DUF3694; 2.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM01052; CAP_GLY; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..345
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1585..1627
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1401..1422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1449..1493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1632..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 357..402
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1471..1493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 95..102
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1687 AA; 187756 MW; C2D15010877AE819 CRC64;
MSSFKYQLLT VILSFLFSFA SRTQPKVRFT LNFHFLVSLQ LILVIFVFAY DYCFWSMDES
QKDKFAGQDV VFQCLGENLL DNAFMGYNAC IFAYGQTGSG KSYTMMGSAE QPGLIPRLSS
SLFSRTVQEA REGESFTVEV SYMEIYNEKV RDLLDPKGSR QALRVREHKV LGPYVDGLSH
LAVASYKDIE SLMSEGNKSR TVAATNMNEE SSRSHAVFNI ILTHTLMDLQ SGTSGEKVSK
LSLVDLAGSE RAAKTGAAGE RLKEGSNINK SLSTLGLVIS ALAEQGAGKN KSKFVPYRDS
VLTWLLKDSL GGNSRTAMVA TISPAADNYD ETLSTLRYAD RAKSIVNHAV VNEDPNARII
RELREEVEKL REQLTEAESM KAPELKERLE ESEKLIQEMM VTWEDKLRKT EAIAQERQKQ
LESLGISLQS SGIRVVDDKC FLVNLNADPA LNELLVYYLK DHTRVGSADS QDIQLCGMAI
QPEHCIIDVL ENNGVMLSPH RNARTCVNGS AVSCPVQLHH GDRILWGNNH FFRSVLVYKL
RSHEDGGAAV KTCLSSDRLE VDPDAASDVS SELSFGYEFA QAEVMMKGMG NNDPLQSVLQ
TLERQHEEEK RCALERQRLM YEQELQQLRQ RLSPEKPTLC RTTFVLWCRE AMMTRSLRRL
REQILRARLL AQEAGFIAEE LNKRTEYLVT LQIPAANLDA NRKRDVVLSE PAIQVRRKGK
GKQIWALEKM ENRLVDMREL YQEWKDFDED NPVMRSYFKR ADPFFDEQEN HSLIGVANVF
LACLFYDVKL QYAVPIINQK GEVAGRLHVE VFRGTEIKYN SVPTVSSSSV LQVKVLQATG
LPRHLSNFVF CQYHFWGQEE PVFTAPEVAP SSSSSASRDP QCTVVFDSEL SVPVSEDFVE
FLAEGAVAIE VYGHKQANHR RNLALWDLGV IQAKTRSLRE RWSEVTRRLE LWVQVMELNE
AGEFTPVEVQ PAKDVRTGGT FQLRQGQSRR VQVEVRSVSD SGTMPLIAAS ILSVSIGDVK
VQQIRHSRND SQWVDLERMR EQWLLTLTQR QEYLDQQLQK IVSKPDKSED DVERESQLLE
CRLTLTEERN AVLVPSAGSG IPGAPVERVP VPGMETHIPV LFLDLSADDF QSSLSAPLAG
GLDALLSRED DDDFFDLHIV KHCDPEVKVE ASWDSTVHEC PQLSRVTSAD QRVYLTVRSV
VQLSHPAHMQ LVLRKRICVN VTGRQGFAQS LLRRMSQRST IPSCGVTFEI VSNIPGDIHG
PEDREMLARL AASAEDDQSA DSEAAIEKYL RSVLAVENVL TLDRLRQEVA VREQLAVRGK
AARRCLSSPD IQRVRSLQAD HLSPLSLAQR MTIGVVALTL EAFQIRLQVS NSIVSMVSSQ
IPTEEVLPST MEPNIPKSVP LPPPIIPETE DSTPSPVSEA SSGYMSTSIS TATLSEVYTL
SWDLPPSLSS RADGFEAVPD EEEEDSKETQ RSSPLYIASQ SNTGPEPLHD SKSVSSVANP
FKIQKVMSSD LKSFQQILGE EEGSLGRASS LGTGLNLSVP MESLEIISDT EEGDAAVSAV
LPDWLKEGEF VTVGANKSGT VRYLGPTDFA EGTWVGVELE VPAGKNDGSV GGKHYFYCNP
GYGVLVRPDR VTRGGAKRRR QQQQKHRSAN LSGSSPNLAA LTALAKGHAG GASSGRSRGE
NRKSWNN
//
