ID A0A3Q1AR71_AMPOC Unreviewed; 482 AA.
AC A0A3Q1AR71;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=TNF receptor-associated factor {ECO:0000256|PIRNR:PIRNR015614};
GN Name=TRAF2 {ECO:0000313|Ensembl:ENSAOCP00000000606.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000000606.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000000606.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR015614}.
CC -!- SIMILARITY: Belongs to the TNF receptor-associated factor family.
CC {ECO:0000256|PIRNR:PIRNR015614}.
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DR AlphaFoldDB; A0A3Q1AR71; -.
DR Ensembl; ENSAOCT00000014648.1; ENSAOCP00000000606.1; ENSAOCG00000003478.1.
DR GeneTree; ENSGT00940000156621; -.
DR OMA; INESCSW; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR012227; TNF_rcpt-assoc_TRAF_met.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR049441; TRAF2_Znf.
DR InterPro; IPR032070; TRAF_BIRC3-bd.
DR InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF160; TNF RECEPTOR-ASSOCIATED FACTOR; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF21341; TRAF2_zf; 1.
DR Pfam; PF16673; TRAF_BIRC3_bd; 1.
DR Pfam; PF02176; zf-TRAF; 1.
DR PIRSF; PIRSF015614; TRAF; 2.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 2.
DR SUPFAM; SSF57953; Trimerization domain of TRAF; 1.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR015614};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRNR:PIRNR015614};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRNR:PIRNR015614};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 99..150
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 332..477
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT ZN_FING 99..150
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT COILED 229..256
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 482 AA; 55312 MW; 75BD3233FB380F99 CRC64;
TTTHNLDCRK NNKPGFPKKI LGNKLEDKHL CNCCHNILRR PFQAQCGHRA VMFILVVSLV
DVEAFPDNAV RREVESLSAV CINESCTWKG SIKDYELNHE GRCEFMIIPC PSCKERIRYN
EQERHNEREC PERTLNCKYC KEPFHFKNIK AHDEICPKYP MICEGCAKKK IPREKVNLEK
TRRPGGSFVM QTEKIHDHER AYAYEHLNLL LHYIMGMKVS MEGLQPQGLE LAGHKLVELQ
QSLRELEARV SQCTELEVKS GTFENVVCVL NREVERFATT MEASNRQHKL DQDKIEALSN
KVRQLERTVG LKDLTVAEME GRLREMSATT FDGVFVWRIS DFAKKRQDAI AGRAPAMFSP
AFYTSKYGYK MCLRIYLNGD GTGRGSHLSL FFVVMRGLSD ALLKWPFNQK VTLMLLDQSN
REHIIDAFRP DVTSSSFQRP VSEMNIASGC PLFCPLSKLD AKNSYIRDDT IFIKAIVDLT
GL
//
