ID A0A3Q1ARA4_AMPOC Unreviewed; 684 AA.
AC A0A3Q1ARA4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Elongation factor for RNA polymerase II 2 {ECO:0000313|Ensembl:ENSAOCP00000003902.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000003902.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000003902.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ELL/occludin family.
CC {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q1ARA4; -.
DR STRING; 80972.ENSAOCP00000003902; -.
DR Ensembl; ENSAOCT00000008984.1; ENSAOCP00000003902.1; ENSAOCG00000007243.1.
DR GeneTree; ENSGT00940000154828; -.
DR OMA; PNYYEEK; -.
DR OrthoDB; 2910197at2759; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0008023; C:transcription elongation factor complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.340; -; 1.
DR Gene3D; 1.10.10.2670; E3 ubiquitin-protein ligase; 1.
DR InterPro; IPR042065; E3_ELL-like.
DR InterPro; IPR031176; ELL/occludin.
DR InterPro; IPR019464; ELL_N.
DR InterPro; IPR010844; Occludin_ELL.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR PANTHER; PTHR23288:SF8; RNA POLYMERASE II ELONGATION FACTOR ELL2; 1.
DR Pfam; PF10390; ELL; 1.
DR Pfam; PF07303; Occludin_ELL; 1.
DR SUPFAM; SSF144292; occludin/ELL-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51980; OCEL; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 570..680
FT /note="OCEL"
FT /evidence="ECO:0000259|PROSITE:PS51980"
FT REGION 305..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..561
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 77034 MW; 8A666F135091896B CRC64;
MLQPQRDDGG GLVKMAALSE DGRYGLNCGQ HSADRVTVLH VKLTETALRA IESYQNCMNV
PSLPPTIQFK GLQGRIKIPK TDSSSETFHS FDFYLSNVGK DNPQGSFECI HQYVSSSGAS
HLALLAAVQD KVTVCATNDS YQVTRERMTQ AVEDTRERGT KVIKPGGQYR GKKVHIRKPA
LSAPEVAPER KRSTPINPAN TIRKCLSNNP VSQRPFRDRI VHLLALRSYK KLEVLARLQR
DGINQKDRNS LGTTLQQVAN LNPKDNTYSL KDFIYRDVQR DWPGYSEDEK SQVDRILTRK
LGLSAETVST SSSPKDGVPT SPQKRQPDFD FIDPLAPKKA RISHLSNRGP VSSSSSSSSD
RREDEGSPSS KRWSLPSNAT SGPPTHLPIS SHPPAPSHQQ PSPASNSNSP STPEGCGTQD
LPMDQSSSCR DPSPSPFSSD RTLQDRYRHP VPRPAGSPSP TPPCTSLTVT STVITSPPLS
SSTHKKFKKK SKKHKDKDRE REKGKRTERE SSIPQSVAKP PEESRRAKKR RSAEEEHREV
ISKNSHKDQD SSDKERPVQA TELSSKIKTP DYVVKYTPLV SNDQRQSYKD DFNAEYDEYR
LLHARVEKIT RRFTQLDTRC RKLVPGTKEY QKVQEEVLKE YKKMKQHSPS YHDEKLRCEY
LHNKLAHIKR LIADFDQRRA QAWC
//
