ID A0A3Q1ATD8_AMPOC Unreviewed; 1321 AA.
AC A0A3Q1ATD8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Crumbs cell polarity complex component 1 {ECO:0000313|Ensembl:ENSAOCP00000004762.1};
OS Amphiprion ocellaris (Clown anemonefish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Amphiprion.
OX NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000004762.1, ECO:0000313|Proteomes:UP000257160};
RN [1] {ECO:0000313|Ensembl:ENSAOCP00000004762.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR Ensembl; ENSAOCT00000007540.1; ENSAOCP00000004762.1; ENSAOCG00000008332.1.
DR GeneTree; ENSGT00940000155152; -.
DR Proteomes; UP000257160; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 13.
DR CDD; cd00110; LamG; 3.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.10.25.10; Laminin; 15.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF31; DELTA_NOTCH LIKE EGF REPEAT CONTAINING; 1.
DR Pfam; PF00008; EGF; 9.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF02210; Laminin_G_2; 3.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 15.
DR SMART; SM00179; EGF_CA; 13.
DR SMART; SM00282; LamG; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 10.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 7.
DR PROSITE; PS00022; EGF_1; 13.
DR PROSITE; PS01186; EGF_2; 9.
DR PROSITE; PS50026; EGF_3; 15.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1259..1285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..81
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 83..119
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 121..157
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 159..196
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 198..234
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 236..292
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 294..336
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 338..378
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 380..568
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 570..606
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 612..784
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 786..822
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 849..1038
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1040..1076
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1078..1113
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1115..1151
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1171..1209
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1211..1247
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1293..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 71..80
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 109..118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 147..156
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 224..233
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 282..291
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 368..377
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 596..605
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 812..821
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1066..1075
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1082..1092
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1103..1112
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1141..1150
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1199..1208
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1237..1246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1321 AA; 144305 MW; 0A3D204F37B7637D CRC64;
NITICSTSMI SNWISFCLES MMPSDVNISK HDLFIGASPD KLPPTVDQCS PNPCQNRAIC
RLRGDGYSCF CVPGFQGARC QIDVNECASE PCSNGATCVD RVGRFSCLCS PGFTGVTCEV
QIDECQSQPC LNGGSCHDYA GGYSCTCLSG FQGHRCEINI DECQEQPCQN GGLCIDGVNE
YSCDCSHSAF TGRHCETPLP PCLSEPCFNS AICKDDHGNY TCECWPGFEG RHCEVDISEC
SSSPCLRGGR CIERSWQALY GSEPLLPEHY DQRQAAGYIC SCPPGTTGSL CQEVINHCES
SPCQNGGRCE SYVGGYICHC LKQSTDGILY GGVNCDVKLV GCEGHECQNQ GSCSPFLLDG
THGYTCSCSP GYTGPLCKTT TTFSFERRGY LLLQSPLVDA NCNITLSFKT VLPRALLFQR
NTRGLLLSLE LDGGQLRLTL RRVASAGAEA EILSQVLEIS QNVTDGEWHS VEAVLGNWLL
SLKLLDDAGS CAGQSCHKVA PVQSTLAGFV SSPQSTFIGG IPQDSKGRSE HSALPAFIGC
MRDVFVDWQL IVPEEWLSDS AINVSPGCSH RDRCLDVPCQ NRGQCVNLWQ SYQCRCPRPY
EGQDCEEEHV TARFGNEDSH SYAAFTITED LGHNLSISLF LRTRRHSGLL LVFSNSSSQY
LHMWLEDGRV TVQLNNYESV KSESTIDDAE VHFVNLEVAE GRMALHVAAE KQGDVEVRTV
DVRAGDTVHV GGLLEKRSTA VFGGYFKGCI QDLRISDRRL QFFGLDTSVR SYPLELMENV
TAGCSGDNAC SRNPCLNGGM CYSTWDDFTC TCPPNTSGRR CEEVRWCELS PCPTDAECRM
LNQGYECYSN ATFLDDSTVL SYQGNGYISR NLTNLSLSLR TRKRNAAILH AEKSSAFITV
SIQDGFLFME LQSTSEGVSP VSLSSRRSVS DGEWHSVHLF MAAPWAQTSR WSLVLDENIE
EASTSKSEGG NLNFLRQGVD IFLGGLAPEA GWSLAGCLST VELGGIALSY LSSSDVNLPR
LQEEQFTQTS LSPALLGCSG APVCEPNPCL NGGECQDLFN TYNCSCTEGW AGRRCDFFLD
TCASNPCVHG NCSINGLTYE CICEFGYTGV DCEEDLDVCE NHLCAHGGTC LHGPDRYACL
CPENYTGPLC NERVEEIPWY IVVKNVRPKL PVSVCGDDTR NYTCFNGGNC TNRELSCDCP
PGFIGHRCEQ EVDECKSNPC LNGGYCRNLI DKFSCVCEMS FAGDLCQTDM TSDGLTSDLL
LSISLVSVIM LLVLILTSVG LVVALNRRAT HGTYSPSRQE KEGSRVEMWS ITQPPPMERL
I
//
