ID   A0A3Q1AY97_AMPOC        Unreviewed;       822 AA.
AC   A0A3Q1AY97;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Protocadherin 2 alpha a 15 {ECO:0000313|Ensembl:ENSAOCP00000006547.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000006547.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000006547.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1AY97; -.
DR   Ensembl; ENSAOCT00000004424.1; ENSAOCP00000006547.1; ENSAOCG00000010182.1.
DR   GeneTree; ENSGT00940000165118; -.
DR   OMA; ELRWIAF; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 6.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR032455; Cadherin_C.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF290; PROTOCADHERIN1-ALPHA-AV15-VCP-RELATED; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF16492; Cadherin_C_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 6.
DR   SUPFAM; SSF49313; Cadherin-like; 6.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        697..720
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          30..135
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          136..244
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          245..352
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          353..458
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          459..569
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          585..683
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   822 AA;  90891 MW;  E6A4095F5CB6A5DD CRC64;
     MEQKRLGVSK EQRRWVAFIV SLTVLWSSAS AQIRYSIAEE VKEGTAVGNI AKDLGLEKNT
     LKERGCRIVE GSTESFFHVN QDDGILYVDR VIDREKVCER SAVCLINLKI VLENPLEIHY
     VTVEVLDVND HSPSFLTKES RLEISESVLP GLRLQLQAAH DADVGQFSVQ EYKLSPNDHF
     RLEVKERGKD GKMPILVLLK TLDRETKKNH KLLLSAIDGG KPSKSGTAEI TVDVLDVNDN
     MPVFKEETYS VLLNENAPIG TTIIKVNASD LDEGSNGDVF YSFGSNVNNR IRELFSVDPN
     TGEIIVQDLI DFEVEESYEI DIQASDKGSA PLRTDKSVLV NIVDLNDNIP QIEVTSFSRA
     VPEDARLGTT VALISVLDKD SGLNGKVICS FNEDVPFTLS PSTQDNMYAI VTKSTLDREK
     QAIFNVRIVA KDAGVPSLSS EKSITIVVSD VNDNSPEFSA SPYTFYIPEN NSPGASLFAV
     KASDRDEGDN SRILYNILRD GKDNTKVHSF NLNINSENGE ILALKSFDFE TLKTFQFQVV
     ATDSGAPSLS SNVTVNVFIL DQNDNAPVIL YPLSSNGSAE GVEDIPRNVN AGHLVTKVRA
     YDADIGYNGW LLFSLQELTD HSLFGLDRYT GQIRTLRSFT ETDETEHKLV ILVKDNGNVS
     LSATATVIVK LVEPKEAFAA SDVKSAAKVD EDDSVTFYLM ITLGSVSVLF LISIIVLIAM
     QCSKSTDYTS KYLQETNYDG TLCHSIQYRS GDKRYMLVGP RMSIGSTIVP GSHANTLVLP
     DRRRASEETK PNMQSAYKMD CVHDGFGSVL ELRFRTIQIF NL
//