ID   A0A3Q1AYY1_AMPOC        Unreviewed;       573 AA.
AC   A0A3Q1AYY1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=FERM domain-containing protein 5-like {ECO:0000313|Ensembl:ENSAOCP00000003086.1};
GN   Name=FRMD5 {ECO:0000313|Ensembl:ENSAOCP00000003086.1};
OS   Amphiprion ocellaris (Clown anemonefish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Amphiprion.
OX   NCBI_TaxID=80972 {ECO:0000313|Ensembl:ENSAOCP00000003086.1, ECO:0000313|Proteomes:UP000257160};
RN   [1] {ECO:0000313|Ensembl:ENSAOCP00000003086.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q1AYY1; -.
DR   STRING; 80972.ENSAOCP00000003086; -.
DR   Ensembl; ENSAOCT00000010385.1; ENSAOCP00000003086.1; ENSAOCG00000006336.1.
DR   GeneTree; ENSGT00940000156346; -.
DR   OMA; IKWNEVA; -.
DR   OrthoDB; 2912597at2759; -.
DR   Proteomes; UP000257160; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd17102; FERM_F1_FRMD3; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR000798; Ez/rad/moesin-like.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR   PANTHER; PTHR23280:SF5; FERM DOMAIN-CONTAINING PROTEIN 5; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257160};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        500..526
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          17..298
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          342..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          451..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        409..428
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        452..466
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   573 AA;  65409 MW;  DB5ABE2F11DF41BF CRC64;
     MLSRLMSSSI RSLDRECNCT VRLLDDSEYT CTIQRDAKGQ YLFDLICHHL NLLEKDYFGI
     RYVDPDKQRH WLEFTKSIAK QMKSQPPFTM CLRVKFYPPD PAALKEEITR YLVFLQVKRD
     LYHGRLLCKT SDAALLAAYI LQAEIGDYDP GKHPEGYSSK FQFFPKHSEK LERRIAEIHK
     TELIGQSPET SELNFLQKAQ MLETYGVDPH PCKDVSGNPA FLAFTPFGFT VLQGNRRVHF
     LKWEEVTKLK FEAKTFHIYA NQKEDKKIIL TYFAPTPEAC KHLWKCGVEN QAFYKLEKSS
     QVRTVSSSNL FFKGSRFRYS GKVAKEVMEQ SAKIKRDPPE IHRAGMVPSR SCPSITHGPR
     LTSVPRTRRR AVHISIMEGL ESLRDSAHST PVRSVSHGDS FMPSRGQMVD GSEASTSAVI
     SDEAYSPSDS VLPTPVAEHG MEPLARHLNG APCSIDEEKD SEAGTSKEGQ AAEFGPGRRA
     LRMVRSRPSP PSDVEELNKF ILSVLRLFLV TIGLLFALLL LLIMLTESDL DIAFLRDIRK
     TPEFQQFHFE YFCPLRRWFA CKLRWMGGFI VSK
//